Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
Willingness and driving factors of rural homestead withdrawal in china's major grain producing areas from the new quality productivity perspective. [PDF]
Zhou H+6 more
europepmc +1 more source
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
Factors affecting the maximum outcome payments of social impact bonds. [PDF]
Wang H, Chao N, Chen J, Chen M, Fu T.
europepmc +1 more source
Evaluation of methods for automatically determining the fitness of currency
D P Stokesberry, I Philmon
openalex +1 more source
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi+2 more
wiley +1 more source
Cost savings of a nationwide project preventing healthcare-associated infections in adult, paediatric and neonatal critical care settings in Brazil: a micro-costing study. [PDF]
Bass LM+14 more
europepmc +1 more source
Measurement of thickness of chromium on currency printing plates :
Fielding Ogburn
openalex +1 more source
Possible role of human ribonuclease dicer in the regulation of R loops
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik+2 more
wiley +1 more source
GTP before ATP: The energy currency at the origin of genes. [PDF]
Mrnjavac N, Martin WF.
europepmc +1 more source