Results 241 to 250 of about 851,212 (362)

Are Economic Evaluations of Task Shifting Too Narrow in Focus? A Rapid Review. [PDF]

Pharmacoeconomics
Murphy P, Griffin S, Fulbright H, Walker S.   +3 more
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Accuracy, Readability, Understandability, and Actionability of ChatGPT Responses to Patient Questions on Systemic Isotretinoin Treatment. [PDF]

Indian Dermatol Online J
Küçük R, Güngör CB, Topal İO, Küçük RB, Karadağ AS.   +4 more
europepmc   +1 more source

Interdependence and Risk Transmission Among Currencies and Equity Markets: Asymmetric Time-Frequency Analysis

Musefiu A. Adeleke, Adeolu O. Adewuyi, Ibrahim A. Adeleke   +2 more
openalex   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

The role of export competitiveness in driving Renminbi cross-border settlement: Micro-level evidence from China. [PDF]

PLoS One
Bu D, Jiang L.
europepmc   +1 more source

Research on the Impact of Digital Currencies on the Internationalisation of the Renminbi and the Role of Promotion

Wenze Ma
openalex   +2 more sources

Machine Learning Based- Fake Currency Detection using SVM and KNN [PDF]

Mohammad Shameera, Mr. G. Srinivasarao, Melisa Sri, M. Kusuma Sri, M. Madhusudhan Reddy   +4 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Can sleep be "banked"? A PRO-CON debate. [PDF]

Sleep
Raizen DM.
europepmc   +1 more source