Results 81 to 90 of about 50,629 (268)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ECONOMIC SECURITY OF CURRENCY DURING PANDEMIC PERIOD

open access: yesВестник Северо-Кавказского федерального университета, 2022
The article provides a description of the position of currencies in the financial market, reflecting the importance for the Russian economy. At the same time, financial activities and the dependence of the ruble exchange rate on oil prices, which give a ...
D. Abakumova   +2 more
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

De-Dollarisation in International Payments: Trend or Fiction

open access: yesECONOMICS
The present research paper is focused the widely debated topic related to de-dollarization. It examines the trend of de-dollarization to check if the statements that the dollar is losing its weight and is about to lose its leading position in ...
Todorova Vesela   +2 more
doaj   +1 more source

CHINESE YUAN EXCHANGE RATE AGAINST THE INDONESIAN RUPIAH PREDICTION USING SUPPORT VECTOR REGRESSION

open access: yesBarekeng
This study aims to forecast the exchange rate between the Chinese Yuan (CNY) and the Indonesian Rupiah (IDR) using Support Vector Regression (SVR), a machine-learning technique that can handle nonlinear and complex data.
Steven Soewignjo   +5 more
doaj   +1 more source

Currency Factors

open access: yesManagement Science, 2017
We examine the ability of existing and new factor models to explain the comovements of G10 currency changes, measured using “currency baskets.” A clustering technique reveals a clear two-block structure in currency comovements, with the first block containing mostly the dollar currencies and the other the European currencies.
Arash Aloosh, Geert Bekaert
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

CHALLENGES AND TRENDS OF BUILDING NEW WORLD ARCHITECTURE WITH BRICS+ COUNTRIES

open access: yesInternational Journal of Law in Changing World
BRICS is a unique multilateral organization spanning Europe, Latin America, Asia, and Africa, playing a key role in shaping a multipolar world. The expanded BRICS+ holds transformative potential by creating alternatives to dominant global systems, such ...
Yulia S. Kharitonova, Anna V. Belitskaya
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

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