Results 101 to 110 of about 162,901 (338)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

An Analysis of Early Warning Signals of Currency Crises in Turkey, 1986-2004 [PDF]

open access: yes
Within a signals approach framework à la Kaminsky, Lizondo and Reinhart, this paper aims both to detect the early warning signals of currency crises in Turkey and to discuss the reliability of an early warning system for this country.
Aykut Kibritçioğlu
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Crises gêmeas nos mercados emergentes: América Latina x Leste Asiático

open access: yesNova Economia, 2009
This article uses a crisis index based on an average of the variations in currency and financial crises indicators, referred to as “twin crises ”, adjusting them to the same volatility.
Tito Belchior Silva Moreira   +2 more
doaj  

Analysis of Linkage Effects among Currency Networks Using REER Data

open access: yesDiscrete Dynamics in Nature and Society, 2015
We modeled the currency networks through the use of REER (real effective exchange rate) instead of a bilateral exchange rate in order to overcome the confusion in selecting base currencies.
Haishu Qiao, Ying Li, Yue Xia
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

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