Results 131 to 140 of about 162,901 (338)

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

SOURCES OF ASIAN CURRENCY CRISIS [PDF]

open access: yes
This study examines the sources of currency crises in ASEAN. The empirical findings indicate that reserve inadequacy, increase of bank’s claims on private sector, deteriorating trade balance and misalignment of real exchange rate increase the probability
Muhd-Zulkhibri Abdul Majid
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

What drives financial crises in emerging markets? [PDF]

open access: yes
The study examines the reasons for financial crises in 31 emerging market countries during 1980-2001. It estimates a probit model using 23 macroeconomic and financial sector variables.
Komulainen, Tuomas, Lukkarila, Johanna
core   +3 more sources

CRISES & CRASHES: ARGENTINA 1885 – 2003 [PDF]

open access: yes
This paper is aimed at studying the determinants of currency crises suffered by Argentina from 1885 to 2003, on one hand, and at characterizing each particular currency crisis, on the other hand.
Ana María Cerro, Osvaldo Meloni
core  

EFECTELE VARIAŢIEI CURSULUI VALUTAR AL MONEDEI NAŢIONALE ASUPRA ECONOMIEI REPUBLICII MOLDOVA: SINTEZA CAUZALĂ

open access: yesStudia Universitatis Moldaviae: Stiinte Umanistice, 2009
This article analyzes the situation on the exchange market of Republic of Moldova for 2000-2009 periods, the factors which caused the national currency appreciation and the effects over the economy in condition of financial and economic crises. Also, we
USM ADMIN
doaj  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Currency Substitution, Seigniorage, and Currency Crises in Interdependent Economies [PDF]

open access: yes, 2003
This paper applies a two-country framework that allows for currency substitution in an environment in which policymakers optimally vary interest rates in light of utility-based objectives, one country pegs the value of its currency to the other nation’s ...
Daniels, Joseph P., VanHoose, David D.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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