Results 171 to 180 of about 162,901 (338)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Exploring nurse staffing and policy implications in times of crisis: the case of North Lebanon. [PDF]

BMC Nurs
Dankar MJ, Yazbik-Dumit N, Ammar W.
europepmc   +1 more source

Is There a Causal Link between Currency and Debt Crises?

, 2005
Axel Dreher, Bernhard Herz, Volker Karb
openalex   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Quality Assessment of Health Information on Social Media During a Public Health Crisis: Infodemiology Study. [PDF]

JMIR Infodemiology
Haghighi R, Farhadloo M.
europepmc   +1 more source

Foreign Currency Debt, Financial Crises and Economic Growth: A Long Run View [PDF]

Foreign currency debt is widely believed to increase risks of financial crisis, especially after being implicated as a cause of the East Asian crisis in the late 1990s.
Chris Meissner, David Stuckler, Michael Bordo   +2 more
core  

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Understanding Drivers of Nurse Migration and Its Consequences Amid the Polycrisis in North Lebanon. [PDF]

Cureus
Dankar MJ, Ammar W.
europepmc   +1 more source

Balance Sheet Effects in Currency Crises: Evidence from Brazil [PDF]

In third generation currency crises models, balance sheet losses from currency depreciations propagate the crises into the real sector of the economy.
Marcio G. P. Garcia, Marcio M. Janot, Walter Novaes   +2 more
core  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source