Results 101 to 110 of about 1,354,476 (351)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

What caused the Asian currency and financial crisis? [PDF]

open access: green, 1999
Giancarlo Corsetti   +2 more
openalex   +1 more source

A case study of a currency crisis: the Russian default of 1998 [PDF]

open access: yes
This paper uses a currency crisis framework to analyze the currency devaluation and debt default of post-Soviet Russia in August 1998. The authors show that even though the Russian economy recorded positive growth immediately preceding the default, the ...
Abbigail J. Chiodo, Michael T. Owyang
core  

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

The Impact of Capital Control on Currency Crises in Developing Countries [PDF]

open access: yesفصلنامه پژوهش‌های اقتصادی ایران, 2010
Capital mobility has been an important part of the economic reforms in many developing countries since the early 1990s, after realization of the benefits of decreasing capital control during 1970s.
seyed komail tayebi, Abbas Mohammadzadeh
doaj  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

Currency Boards In Crisis: Experience Of Baltic Countries

open access: yesWorld academy of science, engineering and technology, 2014
{"references": ["H. Hanke and K. Schuler, Currency Boards for Developing Countries, A\nHandbook, 2000.", "A. R. Ghosh; A-M.Gulde, C. H. Wolf: Exchange Rate Regimes: Choices\nand Consequences, 2002., MIT", "International Monetary Fund, Annual Report on Exchange\nArrangements and Exchange Restrictions, 2013.", "K.
Kordić, Gordana, Palić, Petra
openaire   +2 more sources

An "almost-too-late" warning mechanism for currency crises [PDF]

open access: yes
We propose exploiting the term structure of relative interest rates to obtain estimates of changes in the timing of a currency crisis as perceived by market participants.
Crespo Cuaresma, Jesýs, Slacik, Tomas
core  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

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