Results 151 to 160 of about 7,601,913 (313)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Influence of electrostatics upon electrospray with the intention of application to colloid thrusters [PDF]
, 2011 PhDA thorough experimental and theoretical characterization of the effect of electrostatics on the electrospray process, focusing particularly on the flow rate sensitivity to the applied potential difference (voltage), has been completed.
Ryan, Charles N., Ryan, Charles N
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Cellular Phone Applications by [PDF]
, 2003 An Ultra-Low-Quiescent-Current Dual-Mode Digitally-Controlled Buck Converter IC ...
Dual-mode Digitally-controlled +3 more
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Model of the L-Mode Confinement in Tokamaks [PDF]
, 1992 Model of the L-mode confinement in tokamaks is developed based on the microscopic ballooning mode instability. The anomalous transport coefficients determine the stability below the critical beta against the ideal MHD ballooning instability.
Itoh, S.-I. +4 more
core +1 more source
Mitigation of Single-Event Effects in SiGe-HBT Current-Mode Logic Circuits. [PDF]
Sensors (Basel), 2020 Sarker MAR +8 more
europepmc +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source