Results 51 to 60 of about 1,015,530 (260)

ECCCII-Based Current-Mode Universal Filter with Orthogonal Control of w_o and Q [PDF]

open access: yes, 2014
This paper presents a new current-mode current-controlled four-input five-output universal filter employing one current-controlled current conveyor (CCCII), one electronically tunable CCCII and two grounded capacitors. The proposed configuration provides
Junnapiya, S.   +4 more
core   +1 more source

Carbon Nanotube Based Delay Model For High Speed Energy Efficient on Chip Data Transmission Using: Current Mode Technique

open access: yes, 2014
Speed is a major concern for high density VLSI networks. In this paper the closed form delay model for current mode signalling in VLSI interconnects has been proposed with resistive load termination. RLC interconnect line is modelled using characteristic
Chandel, Rajeevan   +2 more
core   +1 more source

CMCS: Current-Mode Clock Synthesis

open access: yesIEEE Transactions on Very Large Scale Integration (VLSI) Systems, 2017
In a high-performance VLSI design, the clock network consumes a significant amount of power. While most existing methodologies use voltage-mode (VM) signaling, these clock distributions lose a tremendous amount of dynamic power to charge/discharge the large global clock capacitance. New circuit approaches for current-mode (CM) clocking save significant
Riadul Islam, Matthew R. Guthaus
openaire   +4 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Multi-beam 4 GHz Microwave Apertures Using Current-Mode DFT Approximation on 65 nm CMOS

open access: yes, 2015
A current-mode CMOS design is proposed for realizing receive mode multi-beams in the analog domain using a novel DFT approximation. High-bandwidth CMOS RF transistors are employed in low-voltage current mirrors to achieve bandwidths exceeding 4 GHz with ...
Ariyarathna, Viduneth   +7 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Nonlinear switched-current CMOS IC for random signal generation [PDF]

open access: yes, 1993
A nonlinear switched-current circuit is presented that implements a chaotic algorithm for the generation of broadband, white analogue noise. The circuit has been fabricated in a double-metal, single-poly 1.6µm CMOS technology and uses a novel, highly ...
Delgado Restituto, Manuel   +2 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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