Results 91 to 100 of about 1,811,964 (296)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Global Financial and Economic Crisis and its Russian Manifestations [PDF]
Prostranstvennaâ Èkonomika, 2009 Main causes of the current global economic crisis are considered, whose major discrepancy lies in the total capital accumulated by the American economy exceeding the size of capital value, which could have been covered by the revenues of the economy ...
Goryunov A. P.
doaj
Digital Accounting: An Overview of Current Teaching in Accounting Education
, 2023 Muhammad Khaliq Syafie Bin Md Don +2 more
openalex +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
CURRENT ACCOUNT SUSTAINABILITY IN SELECTED TRANSITION COUNTRIES [PDF]
, 2006 Aleksander Aristovnik
openalex +2 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Modern concepts of the equilibrium real exchange rate estimates
Mенаџмент у хотелијерству и туризму, 2014 Ambivalent attitudes of experts and different empirical results, often unsuccessful, as a result of the application of traditional concepts forming the exchange rate contributed to a new wave of research on the equilibrium real exchange rate, which ...
Brankica Pažun
doaj
The Current Practices and Gaps in Forest Accounting System of Ethiopia: A Review
, 2020 Hundessa Adugna
openalex +2 more sources
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source