Results 231 to 240 of about 664,535 (357)

Changes in appetite-related hormones may not necessarily lead to changes in appetite response. [PDF]

Rev Assoc Med Bras (1992)
Meng W, Jiang Z, Li C, Yang J, Su H.
europepmc   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Children with autism spectrum disorder and attention deficit hyperactivity disorder have evidence of sensory nerve degeneration. [PDF]

PLoS One
Gad H, AlObaidi A, Kamal M, Elhag SF, Aden M, Khan A, Baraka A, Bennabhaktula S, Joseph S, Alhamadi AY, Tolefat MA, Alhothi AA, Malik RA.   +12 more
europepmc   +1 more source

Is the U.S. Current Account Deficit Sustainable? And If Not, How Costly is Adjustment Likely To Be?

, 2005
Sebastián Edwards
openalex   +1 more source

Endothelial GPR68 Is Essential for Arteriogenesis and Represents a Therapeutic Target in a Model of Peripheral Artery Disease

Advanced Science, EarlyView.
Endothelial GPR68 is identified as a critical regulator of collateral artery growth in peripheral artery disease. Genetic and pharmacological evidence demonstrates that GPR68 integrates hemodynamic cues to drive monocyte recruitment and inflammatory remodeling, thereby promoting collateral arteriogenesis and tissue perfusion after ischemia ...
Yiyan Song, Senyi Peng, Zhilei Huang, Miao Yu, Mingyue Wu, Yuexin Zhu, Zeyi Zhou, Yongshan Liu, Yalin Zhang, Yu Huang, Zhongxing Wang, Fu‐Li Xiang, Jie Xu   +12 more
wiley   +1 more source

Methylphenidate Treatment and Risk of Psychotic Disorder.

JAMA Psychiatry
Healy C, O'Hare K, Lång U, Metsälä J, Pulakka A, McGrath J, Migone M, Keating D, Romaniuk L, Gyllenberg D, Kajantie E, Perrett G, Hill J, Elwert F, Kelleher I.   +14 more
europepmc   +1 more source

Food Security Outlook for Eastern Africa by 2050: Climate Change Impacts and Population-Driven Demand Gaps. [PDF]

Curr Environ Health Rep
Simane B, Berhane K, Samet J, Oguge O, Atuyambe L, Shah M, Kumie A, Jack D.   +7 more
europepmc   +1 more source

Glutamine Deprivation Triggers Tribbles Homolog 3 Dependent G‐Quadruplex Resolution to Maintain DNA Repair and Tumor Survival

Advanced Science, EarlyView.
Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji, Xuedan Sun, Zhangran Sun, Mengfan Li, Xinyu Cheng, Shuai Tian, Rick F. Thorne, Jinming Li, Guangzhi Liu, Mian Wu, Xiaoying Liu   +10 more
wiley   +1 more source

Physical activity and academic performance in adolescents: a systematic review of intensity, frequency, and mediating factors. [PDF]

J Exerc Rehabil
Jee H.
europepmc   +1 more source

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

Advanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li, Yanan Liu, Meng Zhang, Yiwei Liu, Meiting Liu, Kaishen Zhu, Zhian Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source