Results 51 to 60 of about 1,646,364 (217)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Diagnosis of the status of the anuran collection at La Salle Museum, Bogotá, Colombia
Biota Colombiana, 2019 The anuran collection of the Museo de La Salle is one of the oldest in Colombia, with 2059 specimens collected since 1917. Its age represents a challenge for a thorough quantification of its status, considering that it may not necessarily fit current ...
Julieth Stella Cárdenas Hincapie +1 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
机车电传动In recent years, there have been large-scale incidents of abnormal wear on subway pantographs and catenaries across China, especially in winter. In 2022, more than 30 subway lines nationwide encountered this issue, resulting in economic losses amounting ...
YANG Gang +4 more
doaj
Optimization of fecal sample processing for microbiome study — The journey from bathroom to bench
Journal of the Formosan Medical Association, 2019 Although great interest has been displayed by researchers in the contribution of gut microbiota to human health, there is still no standard protocol with consensus to guarantee the sample quality of metagenomic analysis.
Wei-Kai Wu +6 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A data-driven approach to wireless channel available throughput estimation and prediction
物联网学报, 2023 The rapid development of wireless local area network technology has brought about new challenges that significantly affect the communication quality of wireless channels.Wireless channel quality is crucial for guiding routers in managing sudden ...
Yao XIAO +3 more
doaj +2 more sources
PLoS ONEObjectivesSince the COVID-19 pandemic, more researchers have used to online data collection to recruit participants to research studies. However, one perceived limitation of online data collection is a belief that it results in lower quality data due to ...
Andrew P Bontemps +3 more
doaj +1 more source
International Journal of Population Data Science, 2018 Theme: Data and Linkage Quality Objectives: • To define health data quality from clinical, data science, and health system perspectives • To describe some of the international best practices related to quality and how they are being applied to ...
Catherine Eastwood +3 more
doaj +1 more source