Results 171 to 180 of about 1,829,206 (317)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Durable Thin-Film Porous Transport Electrodes for High Current Density PEM Water Electrolysis. [PDF]

Adv Sci (Weinh)
Young JL, Beltrán DE, Blair SJ, Duarte RPM, Parimuha MR, Yu H, van Eijk L, Reeves KS, Grejtak T, Martinez J, Chao BA, Wrubel J, Kreider ME, Miller EM, Lenef JD, Heinselman KN, Pylypenko S, Cullen DA, Bender G.   +18 more
europepmc   +1 more source

A Bayesian approach to parameter estimation for kernel density estimation via transformations [PDF]

In this paper, we present a Markov chain Monte Carlo (MCMC) simulation algorithm for estimating parameters in the kernel density estimation of bivariate insurance claim data via transformations.
David Pitt, Xueyuan Wu, Qing Liu, Xibin Zhang   +3 more
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Current density impedance imaging

, 2004
Current density impedance imaging (CDII) is a technique that allows non-invasive measurement of sample conductivity. The conventional Electrical Impedance Tomography (EIT) technique suffers from the ill-posedness of this inverse problem.
Ma, Weijing
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Structure-adaptive single-atom nickel catalysts for pure hydrogen peroxide electrosynthesis at industrial current density. [PDF]

Nat Commun
Wang Z, Jia H, Xie A, Li Y, Chen Z, Lu X, Zhao H.   +6 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Classification of current density vector map using transformer hybrid residual network. [PDF]

PLoS One
Zhu L, Yang Y, Yu W, Zeng Q, Zheng Z, Lin Q, Zhao X, Hu Z.   +7 more
europepmc   +1 more source

Computationally efficient quantum-mechanical technique to calculate direct tunnelling gate leakage current in metal-oxide-semiconductor structures

, 2003
We propose a computationally efficient, accurate and numerically stable quantum- mechanical technique to calculate the direct tunneling (DT)gate current in metal-oxide-semiconductor (MOS) structures.
Haque, A, Hakim, MMA
core