Results 31 to 40 of about 784,662 (197)
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Turn-to-turn fault protection technique for synchronous machines without additional voltage transformers [PDF]
, 2017 This paper presents a novel protection technique for the detection of inter-turn faults in synchronous machines. It is based on the calculation of voltage in the stator windings from the usual phases and neutral voltage, typically available in ...
Gyftakis, Konstantinos N. +2 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
FBG-based fibre-optic current sensors for power systems protection : laboratory evaluation [PDF]
, 2009 Conventional differential current unit protection schemes rely on a pair of electronic protection relays that measure current phasors separately at the boundaries of the protected zone.
Booth, Campbell +3 more
core
Environmental protection and the generalized system of preferences : a legal and appropriate linkage? [PDF]
, 2008 This article will question the legality of measures of environmental ‘conditionality’ in the Generalized System of Preferences [GSP] of the European Community [EC].
Switzer, Stephanie
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Development of power system protection based on optical current measurement [PDF]
, 2013 A theoretical evaluation of a novel, all-optical differential current protection scheme employing low voltage piezoelectric transducers, fiber Bragg grating sensors and Rogowski coils is presented in this paper.
Booth, Campbell +5 more
core
Optimization of force-limiting seismic devices connecting structural subsystems [PDF]
, 2016 This paper is focused on the optimum design of an original force-limiting floor anchorage system for the seismic protection of reinforced concrete (RC) dual wall-frame buildings.
Fleischman, Robert B. +4 more
core +1 more source