Results 41 to 50 of about 7,464,161 (289)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Analysis of the external network parameters influence on the operating characteristics of self-excited induction generators

Electrical engineering & Electromechanics
Introduction. Self-excited induction generators (SEIGs) play a vital role in renewable energy systems, particularly in remote regions. However, their performance is highly sensitive to excitation capacitance, rotor speed and load variations, making ...
A. Dilmi, A. Bouzida, N. Yassa, B. Fares
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Total harmonic distortion of an asymmetric quasi-sinusoidal current

MATEC Web of Conferences, 2017
This paper presents the correlation of factors that determine the quality of asymmetric quasi-sinusoidal output current and dynamic losses in the switches of the current generator circuit.
Grebennikov Vitaliy, Ermoeva Irina, Yaroslavtsev Evgeniy   +2 more
doaj   +1 more source

Reduce the Waveform Distortion Using High-Order Harmonical Driving Current for a Vibrator

IEEE Access, 2021
A method to reduce waveform distortion is proposed and experimentally verified for vibrators driven by voice coil motors. In this method, a current including high-order harmonics is synthesized to drive the vibrator. The amplitudes and phases of the high-
Yuntao Qiu, Lu Zhang, Xikai Liu, Liang Chen, Ning Zhang, Xiangdong Liu   +5 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Análisis de la calidad de la energía en un centro de cómputos Analysis of power quality on data center

Ingeniare: Revista Chilena de Ingeniería, 2013
Este trabajo analiza el impacto que provoca, sobre los índices de calidad de la energía eléctrica, un número importante de cargas no lineales pertenecientes a un centro de cómputos y conectadas a una red trifásica.
Juan Antonio Suárez, Guillermo di Mauro, Daniel Anaut, Rubén di Mauro, Jorge L. Strack   +4 more
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