Results 101 to 110 of about 8,283,927 (297)
Test of the Additivity Principle for Current Fluctuations in a Model of Heat Conduction
The additivity principle allows to compute the current distribution in many one-dimensional (1D) nonequilibrium systems. Using simulations, we confirm this conjecture in the 1D Kipnis-Marchioro-Presutti model of heat conduction for a wide current ...
Pablo I. Hurtado +2 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Electron Counting Statistics and Coherent States of Electric Current
A theory of electron counting statistics in quantum transport is presented. It involves an idealized scheme of current measurement using a spin 1/2 coupled to the current so that it precesses at the rate proportional to the current.
Altshuler B. L. +8 more
core +2 more sources
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Critical Current Distribution in Composite Superconductors
It has long been known that for the description of the E(I)-characteristics of composite superconductors a distribution function can be used instead of a power law relation. With this approach, the conductor is represented by a serial connection of short subsections where the electrical resistance of each subsection is given by a parallel connection of
Müller, H. +3 more
openaire +3 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
An approximate analytical solution of a problem concerning the radiation of electromagnetic waves by regular and biconical dipoles with constant and variable complex distributed surface impedance and arbitrary excitation is derived.
Mikhail V. Nesterenko +3 more
doaj +1 more source
Topological study on electrode wells of vertical grounding electrodes of UHVDC
The main body of vertical grounding electrodes of an ultra-high-voltage direct current (UHVDC) converter station is dispersed electrode wells, due to the shielding effect between electrode wells, the arrangement of which is a problem that needs to ...
Wei Chen +5 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source

