Results 21 to 30 of about 4,987,306 (253)

Nanopore Sequencing Technology and Tools for Genome Assembly: Computational Analysis of the Current State, Bottlenecks and Future Directions

open access: yes, 2018
Nanopore sequencing technology has the potential to render other sequencing technologies obsolete with its ability to generate long reads and provide portability.
Alkan, Can   +4 more
core   +2 more sources

Performance evaluation for ML sequence detection in ISI channels with Gauss Markov Noise [PDF]

open access: yes, 2010
Inter-symbol interference (ISI) channels with data dependent Gauss Markov noise have been used to model read channels in magnetic recording and other data storage systems.
Kumar, Naveen   +3 more
core   +4 more sources

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Opportunistic Error Correction for WLAN Applications [PDF]

open access: yes, 2008
The current error correction layer of IEEE 802.11a WLAN is designed\ud for worst case scenarios, which often do not apply. In this paper,\ud we propose a new opportunistic error correction layer based on\ud Fountain codes and a resolution adaptive ADC ...
Schiphorst, Roel   +2 more
core   +3 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Axial Vector Current and Coupling of the Quark in the Instanton Model [PDF]

open access: yes, 2002
We compute the axial vector current, form factor, and coupling for quarks in the instanton liquid model with two light flavors. Non-local current corrections are derived, as required by the effective 't Hooft interaction.
Carter, G. W.
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Multinucleon ejection model for Meson Exchange Current neutrino interactions [PDF]

open access: yes, 2012
A model is proposed to describe pairs or triples of nucleons ejected from nucleus as a result of Meson Exchange Current neutrino interaction. The model can be easily implemented in Monte Carlo neutrino event generators.
Sobczyk, Jan T.
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A practical scheme for error control using feedback [PDF]

open access: yes, 2004
We describe a scheme for quantum error correction that employs feedback and weak measurement rather than the standard tools of projective measurement and fast controlled unitary gates. The advantage of this scheme over previous protocols (for example Ahn
A. V. Oppenheim   +5 more
core   +3 more sources

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