Results 141 to 150 of about 13,074,375 (386)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

The Electric Current (Apart from the Heat Generated). A Bacteriologibal Agent in the Sterilization of Milk and Other Fluids [PDF]

, 1925
James Beattie, Frederick C. Lewis
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Oscillating edge current in polar active fluid

Physical Review E
18 pages, 23 ...
Hiroki Matsukiyo, Jun-ichi Fukuda
openaire   +3 more sources

On a finite difference scheme for solving the non-linear primitive equations for a barotropic fluid with application to the boundary current problem [PDF]

, 1965
Güinter Fischer
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Comparison of computational fluid dynamics and fluid structure interaction models for the performance prediction of tidal current turbines

Journal of Ocean Engineering and Science, 2020
CFD models perform rigid body simulations and ignore the hydroelastic behavior of turbine blades. In reality, the tidal turbine blades deform due to the onset flow.
Mujahid Badshah, Saeed Badshah, Sakhi Jan   +2 more
doaj  

Investigating the recording and accuracy of fluid balance monitoring in critically ill patients

Southern African Journal of Critical Care, 2014
Background. The accurate assessment of fluid balance data collected during physical assessment as well as during monitoring and record-keeping forms an essential part of the baseline patient information that guides medical and nursing interventions aimed
Annette Diacon, J Bell
doaj   +1 more source

Instability of a Current-Carrying Fluid Jet Issuing from a Nozzle [PDF]

, 1963
Mahinder S. Uberoi, Chuen‐Yen Chow
openalex   +1 more source