Results 181 to 190 of about 13,282,280 (382)

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Effects of Hall Current and Rotation on Unsteady MHD Couette Flow in the Presence of an Inclined Magnetic Field

Journal of Applied Fluid Mechanics, 2012
Unsteady hydromagnetic Couette flow of a viscous incompressible electrically conducting fluid in a rotating system in the presence of an inclined magnetic field taking Hall current into account is studied.
Gauri Shanker Seth, R. Nandkeolyar, Md.S. Ansari   +2 more
doaj  

Heat transfer in a fluidized counter current bed. Annual report, July 1977-July 1978

, 1978
R. Jackson
openalex   +2 more sources

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

FEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Current drilling fluids for deep wells.

, 1986
Morihiro Sano
openalex   +2 more sources

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Erratum: Current drive with fast phase velocity lower-hybrid waves [Phys. Fluids 2 9, 599 (1986)]

, 1986
Viktor K. Decyk, Hirotada Abe
openalex   +1 more source

Cluster observations of an intense normal component of the electric field at a thin reconnecting current sheet in the tail and its role in the shock‐like acceleration of the ion fluid into the separatrix region [PDF]

, 2005
J. R. Wygant, C. A. Cattell, R. L. Lysak, Y. Song, J. Dombeck, J. McFadden, F. S. Mozer, C. W. Carlson, G. K. Parks, E. Lucek, A. Balogh, M. André, H. Rème, M. Hesse, C. Mouikis   +14 more
openalex   +1 more source

Employing Adult Learning Principles for Faculty Development of Equity Focused Teaching: Critical Reflections

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This manuscript describes the intentional use of adult learning principles in creating three faculty development initiatives centering on equity‐based teaching. The authors reflected on the design and development process, facilitation and the perceived benefits and challenges.
Kayon Murray‐Johnson, Melissa A. Willis   +1 more
wiley   +1 more source