Results 31 to 40 of about 273,560 (124)
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Molecular Oncology, EarlyView.Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi +6 more
wiley +1 more source
Machine Learning for Fluid Mechanics [PDF]
, 2019 The field of fluid mechanics is rapidly advancing, driven by unprecedented volumes of data from field measurements, experiments and large-scale simulations at multiple spatiotemporal scales. Machine learning offers a wealth of techniques to extract information from data that could be translated into knowledge about the underlying fluid mechanics ...
arxiv +1 more source
Optimal Control of Fluid Dosing in Hemorrhage Resuscitation [PDF]
arXiv, 2023 Fluid resuscitation, also called fluid therapy, is commonly used in treatment of critical care patients. Of the variables inherent to fluid therapy treatment, fluid infusion types are well-studied, but volumetric optimization is not. Automated fluid resuscitation systems employ computational control algorithms along with physiological sensors and ...
arxiv
Molecular Oncology, EarlyView.This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina +17 more
wiley +1 more source
Capillary-Gravity Waves on Depth-Dependent Currents: Consequences for the Wave Resistance [PDF]
, 2011 We study theoretically the capillary-gravity waves created at the water-air interface by a small two-dimensional perturbation when a depth-dependent current is initially present in the fluid. Assuming linear wave theory, we derive a general expression of the wave resistance experienced by the perturbation as a function of the current profile in the ...
arxiv +1 more source
FluidLab: A Differentiable Environment for Benchmarking Complex Fluid Manipulation [PDF]
arXiv, 2023 Humans manipulate various kinds of fluids in their everyday life: creating latte art, scooping floating objects from water, rolling an ice cream cone, etc. Using robots to augment or replace human labors in these daily settings remain as a challenging task due to the multifaceted complexities of fluids.
arxiv
Molecular Oncology, EarlyView.Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
Chaos Phenotypes in Fluids [PDF]
arXiv, 2008 I shall briefly survey the current status on more rigorous studies of chaos in fluids by focusing along the line of chaos phenotypes: sensitive dependence on initial data, and recurrence.
arxiv