Results 101 to 110 of about 7,175,619 (255)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Mixed-Mode Third-Order Quadrature Oscillator Based on Single MCCFTA [PDF]
Radioengineering, 2017 This paper presents a new mixed-mode third-order quadrature oscillator based on new modified current-controlled current follower transconductance amplifier (MCCFTA).
K. Khaw-Ngam, M. Kumngern, F. Khateb
doaj
Temperature Insensitive Current-Mode Four Quadrant Multiplier Using Single CFCTA
MATEC Web of Conferences, 2017 A four quadrant multiplier of two current input signals using active building block, namely current follower cascaded transconductance amplifier (CFCTA) is presented in this paper.
Tuntrakool Sunti +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Current limiters using single current follower and applications to precision rectifiers
, 2011 284-287A synthesis of current limiters (CLs) using single current follower (CF) is described. The breakpoint of the resulting transfer characteristic obtained from the proposed CF-based CLs is electronically adjustable through an external control ...
Tangsrirat, Worapong
core
A NEW CURRENT TUNABLE CURRENT INPUT CURRENT OUTPUT BIQUAD USING CFTAS [PDF]
Journal of Engineering Science and Technology, 2017 A new current-tunable current input current output universal biquad circuit synthesized with three current follower trans-conductance amplifiers (CFTAs) and two grounded capacitors is presented in this paper. The proposed circuit simultaneously, realizes
S. V. SINGH, R. S. TOMAR, D. S. CHAUHAN
doaj
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Differentiating leader-follower and avoidance interactions [Dataset]
A The method detects a relationship with a KS-arrow from individual B to individual A, which could represent a leader-follower (A as leader, B as follower) or an avoidance (A avoiding B) interaction. B and C show the average appearance rates of A after B
Eguíluz, Víctor M. +5 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Modified current follower-based immittance function simulators
, 2017 In this paper, four immittance function simulators consisting of a single modified current follower with single Z- terminal and a minimum number of passive components are proposed. The first proposed circuit can provide +L parallel with +R and the second
Erkan Yuce +3 more
core +1 more source