Results 91 to 100 of about 3,825,314 (291)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Current protection [PDF]

open access: yesIEEE International Conference on Electro/Information Technology, 2014
Steven Phillips   +2 more
openaire   +1 more source

Risks, designs, and research for fire safety in spacecraft [PDF]

open access: yes
Current fire protection for spacecraft relies mainly on fire prevention through the use of nonflammable materials and strict storage controls of other materials.
Friedman, Robert   +2 more
core   +1 more source

Rotor burst protection criteria and implications [PDF]

open access: yes, 1977
Current aircraft design practices to minimize the hazard from rotor bursts are described. The consequences of non-contained engine failures and the impact of rotor burst protection systems on aircraft design are ...
Mccormick, R. B.
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Method for Detection and Limitation of Short-Circuit Currents for Semiconductor Circuit Breakers in LVDC Grids Using a Pre-Saturated Inductor

open access: yesIEEE Open Journal of Power Electronics
This paper introduces an innovative non-destructive device designed to detect and limit short-circuit currents in LVDC grids. The proposed solution utilizes a transformer fully saturated by a permanent magnet during normal operation. When a short-circuit
Johannes Gehring   +5 more
doaj   +1 more source

Analysis of existing effectiveness and method to enhance the lightning, shielding and earthing protection schemes applied on the Parit Raja’s Telecommunication Tower System [PDF]

open access: yes, 2013
Lightning, one of nature’s most destructive forces, continues to wreck havoc on lives and property especially in today’s electronic environment. It has been shown by field experiences that telecommunication towers are one of the preferential points
Mohd Kasim, Ct Valkyis
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

An Optimized Scheme for Active Distribution Network Current Speed Protection Setting Considering Tie Switch Operation

open access: yesZhongguo dianli
Active distribution grid with tie switches has a complex grid structure and undergo frequent changes in operation mode, which greatly affects the correct operation of traditional current protection that relies on static grid topology and fixed operation ...
Nuo CHENG   +5 more
doaj   +1 more source

Serbia: Current Risks in Heritage Protection

open access: yes, 2017
Heritage at Risk, H@R 2014 ...
Roter-Blagojević, Mirjana   +2 more
openaire   +2 more sources

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