Results 41 to 50 of about 929,929 (317)

Potential of Bacillus pumilus Bp4185 and Bacillus thuringiensis Bt3971 for coffee berry borer biocontrol

open access: yesBiotecnología Vegetal, 2020
Coffee berry borer (Hypothenemus hampei), is one of the main pests affecting coffee production worldwide. This pest feeds and reproduces inside the berry reducing its weight and quality, causing losses up to 50%.
Dainette Vazquez   +2 more
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

INVESTIGATION OF BLOCKING ALGORITHM FOR TRANSFORMER CURRENT PROTECTIONS IN MAGNETIZING INRUSH CURRENT MODES

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2014
Presents investigations on blocking  algorithm for transformer  current  protections  during magnetizing  inrush  current. The investigations have shown that the algorithm has high sensitivity and reliably determines magnetizing  inrush current modes.
A. N. Kuzovlev   +2 more
doaj  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Proteção catódica de estruturas de concreto

open access: yesRevista IBRACON de Estruturas e Materiais
A adoção de técnicas de proteção às estruturas do concreto é recomendada quando há preocupação com a corrosão das armaduras de aço-carbono. Dentre as principais técnicas, destaque-se a proteção catódica que pode tanto evitar a corrosão prematura como ...
A. Araujo, Z. Panossian, Z. Lourenço
doaj   +1 more source

Mechanisms of the IAA and ACC-deaminase producing strain of Trichoderma longibrachiatum T6 in enhancing wheat seedling tolerance to NaCl stress

open access: yesBMC Plant Biology, 2019
Background Trichoderma species, a class of plant beneficial fungi, may provide opportunistic symbionts to induce plant tolerance to abiotic stresses.
Shuwu Zhang, Yantai Gan, Bingliang Xu
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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