Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner+7 more
wiley +1 more source
Pengaruh Current Ratio, Total Asset Turn Over, Dan Net Profit Margin Terhadap Return on Asset Pada Perusahaan Subsektor Makanan Dan Minuman Yang Terdaftar Di Bei Pada Tahun 2012-2016 [PDF]
The purpose of this study is to describe To understand (1) the influence of current ratio, total asset turnover, net profit margin collectively to return on aseet, (2) influence of current ratio to return on aseet (3) influence of total asset turnover to
tyas, E. P. (eria)
core
Evolution of the Kippenhahn-Schlueter Prominence Model Magnetic Field Under Cowling Resistivity [PDF]
We present the results from 1.5D diffusion simulations of the Kippenhahn-Schlueter prominence model magnetic field evolution under the influence of the ambipolar terms of Cowling resistivity.
Hillier, Andrew+2 more
core +2 more sources
Impact of Short-Term Solvency on Operational Efficiency: A Study on Cement Industry [PDF]
The purpose of this paper is to measure/assess the link between short-term solvency and operational efficiency of selected cement companies in India. The researcher has collected, compiled and analysed publicly available data.
Dr. Biswajit Prasad Chhatoi
doaj
Determination of Cooper pairs and Majorana fermions currents ratio in DC-SQUID with topologically nontrivial barriers [PDF]
We present the results of numerical study of the phase dynamics of the DC-SQUID with topologically trivial and nontrivial barriers. In our calculations we take into account two components of supperconducting current, Cooper pairs ($2\pi$-periodic) and Majorana fermions ($4\pi$-periodic) currents. Magnetic field dependence of return current is presented.
arxiv +1 more source
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang+2 more
wiley +1 more source
Korelasi Debt to Equity Ratio, Current Ratio, Total Asset Turn Over Dan Net Profit Margin Dengan Earning Per Share Pada Perusahaan Otomotif Di Bursa Efek Indonesia [PDF]
This research use free Variable The Variable is Debt To Equity Ratio, Current Ratio, Total Asset of Turn Over and of Net Profit Margi and also as Variable tied of that is Earning Per Share (Eps).
Akbar, D. F. (dan), Sjafii, H. (H)
core
Return saham represent one of factors to motivate investor and represent reward of invesment which share done. Return can assess from level of basal factor company specified period.
Dahli Suhaeli Suhaeli, Sartono Tri Tri
doaj
Debtor’s and creditor’s stronghold: Bankruptcy chapter 7, 11 & 13 [PDF]
Bankruptcy law is created to protect debtors from the hands of creditors. This law ensures creditors repay loans by engaging in a particular process. The United States Congress has enacted a decree governing bankruptcy in the form of the Bankruptcy Code.
Faith Cajudo Orillaza
doaj +1 more source
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg+2 more
wiley +1 more source