Results 31 to 40 of about 162,130 (269)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Linking Turbulent Interplanetary Magnetic Field Fluctuations and Current Sheets

open access: yesUniverse
The study aims to understand the role of solar wind current sheets (CSs) in shaping the spectrum of turbulent fluctuations and driving dissipation processes in space plasma.
Maria O. Riazantseva   +5 more
doaj   +1 more source

Magnetic Reconnection in the Martian Magnetotail: Occurrence Rate and Impact on Ion Loss

open access: yesGeophysical Research Letters, 2023
The current sheet is crucial in releasing magnetic free energy in cosmic plasmas via fast magnetic reconnection or wave excitation. This research investigates the characteristics of the Martian tail current sheet by analyzing data acquired from the Mars ...
Lei Wang   +6 more
doaj   +1 more source

Origin of the Warped Heliospheric Current Sheet [PDF]

open access: yesScience, 1980
The warped heliospheric current sheet for early 1976 is calculated from the observed photospheric magnetic field by a potential field method. Comparisons with measurements of the interplanetary magnetic field polarity for early 1976 obtained at several locations in the heliosphere by Helios 1, Helios 2, Pioneer 11, and at the earth show a rather ...
J M, Wilcox   +2 more
openaire   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Quasi‐adiabaticity in bifurcated current sheets [PDF]

open access: yesGeophysical Research Letters, 2006
We examine the non‐linear dynamics of charged particles in “bifurcated” (double‐humped) current sheets. We show that, when the adiabaticity parameter κ is of the order unity, particles experience a negligible change of magnetic moment. Such a behavior contrasts with the prominent magnetic moment scattering that is achieved in single‐humped current ...
Delcourt, Dominique, C.   +2 more
openaire   +3 more sources

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Electron scale structures of thin current sheets in magnetic reconnection [PDF]

open access: yesAnnales Geophysicae, 2012
An electron-magnetohydrodynamic model is used to simulate the structure of an electron scale current sheet during early phase of collisionless magnetic reconnection. The current sheet develops structures, viz.
N. Jain   +3 more
doaj   +1 more source

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