Results 31 to 40 of about 5,118,195 (304)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Current Situation, Global Potential Distribution and Evolution of Six Almond Species in China

open access: yesFrontiers in Plant Science, 2021
Almond resources are widely distributed in Central Asia; its distribution has not been studied in detail. Based on the first-hand data of field investigation, climate variables and chloroplast genome data, climatic characteristics of six almond species ...
Wei Wang   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

PROTECTING AND PROMOTING THE RIGHT TO FREEDOM OF RELIGION AND BELIEF FOR ALL: Challenges and Opportunities

open access: yesSur: International Journal on Human Rights, 2019
Freedom of thought, conscience, and religion or belief (FoRB) is one of the cornerstones of pluralism, and growing evidence indicates that respect for religious pluralism is indispensable to peace and security.
Ahmed Shaheed
doaj  

Prevalence of dental caries among the primary and middle school students in a district of Hangzhou City, Zhejiang Province, in the 2020 school year

open access: yesShanghai yufang yixue
ObjectiveTo understand the prevalence of dental caries among the primary and middle school students in Yuhang District, Hangzhou City, in order to provide a basis for reducing the prevalence and preventing dental caries, as well as providing data support
FANG Hangyan, LEI Chao
doaj   +1 more source

SWOT Analysis for Current Situation in Najaf Center [PDF]

open access: yesEngineering and Technology Journal, 2012
This paper presents an analysis situation of Najaf Center. It uses to determine all internal resources, capabilities and obstacles (strengths and weakness), and external factors (opportunities and threats).
Abdul Razzak Ziboon   +2 more
doaj   +1 more source

Ovine Neosporosis: The Current Global Situation

open access: yesAnimals, 2022
In the past 20 years, Neospora caninum infection in sheep has been reported in at least 31 countries worldwide from all sheep-rearing continents (Europe, Asia, the Americas, Africa, and Oceania), and its role as an abortifacient agent is becoming more evident.
Julio Benavides   +5 more
openaire   +4 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The European Economy: Current Situation and Economic Outlook [PDF]

open access: yes
This chapter presents forecasts of growth and inflation in the European economy for the year 2003 and assesses the current macroeconomic conditions for the whole area and for some individual countries.
Giancarlo Corsetti   +8 more
core   +6 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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