Results 181 to 190 of about 54,038 (216)

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Information Entropy Metrics to Address the Complexity of Cooperative Gating of Ion Channels. [PDF]

Entropy (Basel)
Wawrzkiewicz-Jałowiecka A, Trybek P, Wojcik M, Borys P.   +3 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

KCNJ4 variants disrupt inward-rectifier potassium channel function and cause refractory epilepsy. [PDF]

Epilepsia
Pan H, Liu D, Xu W, Li Y, Hu J, Henry O, Fuchs A, Jamra RA, Liu Z, He M, Chen Y, Wu S, Dong X, Chen Y, Wang P, Gu W, Jing H, Tang Y, Wang YJ, Mao X, Xiao N.   +20 more
europepmc   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Cilia-driven surface currents characterize specific cnidarian groups and lifecycle stages. [PDF]

Commun Biol
Koch T, Araslanova K, Bouderlique T, Fetisov A, Link O, Klimovich A, Mičić M, Mičić K, Boström J, Frade P, Abed-Navandi D, Adameyko I.   +11 more
europepmc   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Global climatology of submesoscale restratification using machine learning. [PDF]

Sci Rep
Yao L, Taylor JR.
europepmc   +1 more source

Empowering Adult Learning How AI Fuels Progress Across Disciplines and Professions

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of artificial intelligence (AI) as a transformative cognitive partner across educational and professional fields. It explores how AI shifts attention away from routine technical tasks and toward human‐centered skills such as critical thinking, ethical decision‐making, and professional judgment.
Rachel Wlodarsky
wiley   +1 more source

High productivity and multilayered circulation in the Late Cretaceous Arctic Ocean. [PDF]

Sci Adv
Liu S, Van Rooij D, Chen M, Fan H, Li G, Shi Y, Liu Y, Ng ZL, Luo K, Lin L, Zhuo H.   +10 more
europepmc   +1 more source