Results 161 to 170 of about 1,083,966 (327)

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Semi‐supervised classification of fundus images combined with CNN and GCN

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose Diabetic retinopathy (DR) is one of the most serious complications of diabetes, which is a kind of fundus lesion with specific changes. Early diagnosis of DR can effectively reduce the visual damage caused by DR. Due to the variety and different morphology of DR lesions, automatic classification of fundus images in mass screening can ...
Sixu Duan   +8 more
wiley   +1 more source

Contravariant Curvatures of Doubly Warped Product Poisson Manifolds

open access: yesMathematics
In this paper, we investigate the sectional contravariant curvature of a doubly warped product manifold ( fB×bF,g˜,Π=ΠB+ΠF) equipped with a product Poisson structure Π, using warping functions and sectional curvatures of its factor manifolds (B,g˜B,ΠB ...
Foued Aloui   +2 more
doaj   +1 more source

Comparison geometry of manifolds with boundary under a lower weighted Ricci curvature bound [PDF]

open access: yesarXiv, 2016
We study Riemannian manifolds with boundary under a lower weighted Ricci curvature bound. We consider a curvature condition in which the weighted Ricci curvature is bounded from below by the density function. Under the curvature condition, and a suitable condition for the weighted mean curvature for the boundary, we obtain various comparison geometric ...
arxiv  

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti   +8 more
wiley   +1 more source

COMP Report: CPQR technical quality control guidelines for use of positron emission tomography/computed tomography in radiation treatment planning

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Positron emission tomography with x‐ray computed tomography (PET/CT) is increasingly being utilized for radiation treatment planning (RTP). Accurate delivery of RT therefore depends on quality PET/CT data. This study covers quality control (QC) procedures required for PET/CT for diagnostic imaging and incremental QC required for RTP.
Ran Klein   +7 more
wiley   +1 more source

Research on Multi-Core Curvature Sensing Measurement Based on PPP-BOTDA

open access: yesSensors
To address the issue of spatial resolution limitations in traditional Brillouin optical time-domain analysis systems due to phonon lifetime constraints, we employed pre-pumped pulse technology.
Zijuan Liu   +3 more
doaj   +1 more source

Rigidity of Riemannian manifolds with positive scalar curvature [PDF]

open access: yesarXiv, 2017
For the Bach-flat closed manifold with positive scalar curvature, we prove a rigidity result under a given inequality involving the Weyl curvature and the traceless Ricci curvature. Moveover, under an inequality involving $L^{\frac{n}{2}}$-norm of the Weyl curvature, the traceless Ricci curvature and the Yamabe invariant, we also provide a similar ...
arxiv  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

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