Results 41 to 50 of about 26,863 (267)

Curvatures of hypersurfaces

Lietuvos Matematikos Rinkinys, 2010
In this article we generalize some classical formulas for curvatures of hypersurfaces in the n-dimensional Euclidean space using the homogeneous formulas.
Kazimieras Navickis
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Spatial Generalized Octonionic Curves

Axioms
This study investigates curves in a 7-dimensional space, represented by spatial generalized octonion-valued functions of a single variable, where the general octonions include real, split, semi, split semi, quasi, split quasi, and para octonions.
Mücahit Akbıyık, Jeta Alo, Seda Yamaç Akbıyık   +2 more
doaj   +1 more source

Geometrical Classification of Self-Similar Motion of Two-Dimensional Three Point Vortex System by Deviation Curvature on Jacobi Field

Advances in Mathematical Physics, 2021
In this study, we geometrically analyze the relation between a point vortex system and deviation curvatures on the Jacobi field. First, eigenvalues of deviation curvatures are calculated from relative distances of point vortices in a three point vortex ...
Yuma Hirakui, Takahiro Yajima
doaj   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

Inverse Designing Surface Curvatures by Deep Learning

Advanced Intelligent Systems
Smooth and curved microstructural topologies found in nature—from soap films to trabecular bone—have inspired several mimetic design spaces for architected metamaterials and bio‐scaffolds.
Yaqi Guo, Saurav Sharma, Siddhant Kumar
doaj   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

Horizon and curvature

Annals of the Academy of Romanian Scientists Series on Mathematics and Its Application, 2023
This short paper is devoted to a strange looking question: is it possible to deduce the shape of a smooth convex set by measuring at each point the distance of the horizon standing at a fixed height h? The question is surprisingly difficult and we only have partial results.
Alain Haraux, Seenith Sivasundaram, Mani Mallika Arjunan   +2 more
openaire   +2 more sources

Distinct cytoskeletal proteins define zones of enhanced cell wall synthesis in Helicobacter pylori

eLife, 2020
Helical cell shape is necessary for efficient stomach colonization by Helicobacter pylori, but the molecular mechanisms for generating helical shape remain unclear. The helical centerline pitch and radius of wild-type H.
Jennifer A Taylor, Benjamin P Bratton, Sophie R Sichel, Kris M Blair, Holly M Jacobs, Kristen E DeMeester, Erkin Kuru, Joe Gray, Jacob Biboy, Michael S VanNieuwenhze, Waldemar Vollmer, Catherine L Grimes, Joshua W Shaevitz, Nina R Salama   +13 more
doaj   +1 more source