Results 181 to 190 of about 2,211,298 (217)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

A predictive model for low-dose rituximab response in anti-acetylcholine receptor antibody-positive myasthenia gravis: establishment and validation. [PDF]

Front Immunol
Hou C, Zhang Y, Cao X, Tang Y, Gao T, Tang B, Zhu Y, Ruan Z, Chang T.   +8 more
europepmc   +1 more source

Identification of risk factors and development of a predictive model for foetal growth restriction: a retrospective case-control study. [PDF]

Ann Med
Shao XF.
europepmc   +1 more source

Real-time detection of extravasation events of diagnostic and therapeutic radiopharmaceuticals in oncology. [PDF]

PLoS One
Cucurachi N, Fioroni F, Grassi E, Panico N, Verzellesi L, Botti A, Fraternali A, Roncali M, Durmo R, Filice A, Iori M.   +10 more
europepmc   +1 more source

Construction and Validation of Active Case-Finding Tool in Community Participants with Chronic Obstructive Pulmonary Disease Using an Interpretable Machine Learning Approach. [PDF]

Int J Chron Obstruct Pulmon Dis
Tian H, Wu F, Sun C, Deng Z, Zhou Y, Ran P.   +5 more
europepmc   +1 more source

The geometric role of the time parameter in DNA base-pair genetic information exchange and assembly: applications of Frenet-Serret formulas to circular and elliptical helix models. [PDF]

RSC Adv
Chen MR, Diño WA, Palazzetti F, Kasai T.   +3 more
europepmc   +1 more source