Results 141 to 150 of about 355,580 (298)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Improved maximum likelihood method for P-S-N curve fitting method with small number specimens and application in T-welded joint. [PDF]
Sci Rep, 2023 Liu W, Zhang L, He L, Liu H.
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Curve-Fitting Algorithm for the Inspection of Subtle Feature Lines on Automotive Outer Panels. [PDF]
Materials (Basel), 2022 Lee CW, Chung YC.
europepmc +1 more source
Practical Handbook of Curve Fitting [PDF]
, 1994 First volume in a three-part series. Book written by Sandra Lach Arlinghaus. Material underwent extensive classroom testing (pre and post publication in handbook form) in course created and taught by W. D. Drake and S. L.
Nystuen, John D. +3 more
core
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
THE CPA QUALIFICATION METHOD BASED ON THE GAUSSIAN CURVE FITTING
Jurnal Informatika, 2015 The Correlation Power Analysis (CPA) attack is an attack on cryptographic devices, especially smart cards. The results of the attack are correlation traces.
M.T. Adithia
doaj
Deterministic Modeling for Radiation Attenuation-integrated Radon Transform in Emission Computed Tomography: Algorithm, Curve Fitting Analysis, and Introduction of Attenuation Hadamard Matrix. [PDF]
J Med Phys, 2023 Qutbi M.
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Curve fitting and jump detection on nonparametric regression with missing data. [PDF]
J Appl Stat, 2023 Li Q, Li J, Cheng Y, Zhang R.
europepmc +1 more source