Results 171 to 180 of about 355,580 (298)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Enhanced Quantitative Assessment of Lumbar Facet Joint Degeneration: Refining the Joint Degeneration Grading System With Grayscale Curve Fitting and Imaging Parameter. [PDF]

JOR Spine
Liu X, Sun M, He S, Zhang H, Li R, Shi J, Ma X.   +6 more
europepmc   +1 more source

Spatial heterogeneity affects predictions from early-curve fitting of pandemic outbreaks: a case study using population data from Denmark. [PDF]

R Soc Open Sci, 2022
Heltberg ML, Michelsen C, Martiny ES, Christensen LE, Jensen MH, Halasa T, Petersen TC.   +6 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Neural spike compression through salient sample extraction and curve fitting dedicated to high-density brain implants. [PDF]

Commun Eng
Nekoui M, Sodagar AM.
europepmc   +1 more source

Stock prediction and mutual fund portfolio management using curve fitting techniques. [PDF]

J Ambient Intell Humaniz Comput, 2021
Maji G, Mondal D, Dey N, Debnath NC, Sen S.   +4 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

B-spline curve fitting based on dynamic adjustment of knot vector using feature points. [PDF]

PLoS One
Chen X, Guo S, Wang R, Zhang C, Lin J, Chen S.   +5 more
europepmc   +1 more source

Constant Potential Coulometric Measurements with Ca²⁺-Selective Electrode: Analysis Using Calibration Plot vs. Analysis Using the Charge Curve Fitting. [PDF]

Sensors (Basel), 2022
Bondar A, Mikhelson K.
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source