Results 211 to 220 of about 1,745,742 (268)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Coarse-Grained Modeling and Interpretation of Phenomenological Creep Rate Behavior with Experimental Validation. [PDF]

Entropy (Basel)
Gong T, Zhou D, Guan X, Du YM.
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Δ-β2M as a dynamic biomarker for predicting ICU admission after CAR T-cell therapy. [PDF]

Ann Hematol
Angleitner AC, Maulhardt M, Thomson K, Büntzel J, Wulf G.   +4 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

A Novel Nomogram for Predicting Osteoporotic Vertebral Compression Fractures with Hounsfield Unit and Vertebral Bone Quality: A Retrospective Cohort Study. [PDF]

Clin Interv Aging
Zhuang C, Yang X, Wang H, Wang Z, Bao F, Yan Z, Lin H.   +6 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Robotic versus laparoscopic intracorporeal anastomosis learning curve: a systematic review. [PDF]

J Robot Surg
Dhadlie S, Larkins K, Fay T, Proud D, Warrier S, Heriot A, Mohan H.   +6 more
europepmc   +1 more source

Wild Galois representations: elliptic curves with wild cyclic reduction. [PDF]

Res Number Theory
Coppola N.
europepmc   +1 more source