Results 191 to 200 of about 102,332 (240)

Intracellular Aβ42 Sequestration by a Serine Protease Mitigates Neurotoxicity in a Drosophila Alzheimer's Disease Model

Advanced Science, EarlyView.
Emerging evidence suggests that intraneuronal Aβ accumulation represents an early pathogenic event in Alzheimer's disease (AD). Using Drosophila AD model, this study shows that a nonsecreted serine protease Yip7 physically interacts with Aβ. This causes intraneuronal Aβ accumulation but surprisingly reduces the associated neurotoxicity, arguing that ...
Jingyun Su, Meng Yang, Xinfeng Wang, Pa Wu, Zongzhao Zhai   +4 more
wiley   +1 more source

Evolution of Cardiac Models Toward Recreating Biologically Relevant Multiaxial Mechanical Stimuli. [PDF]

Tissue Eng Part B Rev
Dey A, Klouda L, Saraf A.
europepmc   +1 more source

Brain‐Adhesive Bioelectronics With Shape‐Morphable and Biodegradable Properties for Stable Brain Signal Monitoring

Advanced Science, EarlyView.
A brain‐adhesive sensor (B‐Sensor) was developed by integrating a self‐healing biodegradable elastomer, a tissue‐adhesive hydrogel, and molybdenum electrodes. The B‐Sensor adheres to brain tissue, conforms to cortical curvatures, and maintains stable electrical performance over the intended period for reliable recording of spatiotemporal brain activity
Heewon Choi, Soeun Kim, Sumin Kim, Jaehyun Park, Soojung An, Sungjun Yoon, Mikyung Shin, Sangho Cho, Donghee Son   +8 more
wiley   +1 more source

Rapid loss of viability in acute myeloid leukemia cells upon telomerase inactivation. [PDF]

Blood Adv
Aquilanti E, Kageler L, Bozinov V, Meyerson M.   +3 more
europepmc   +1 more source

Polymer Matrix‐Based 3D Culture Significantly Enhances the Differentiation and Immunomodulatory Functions of Human Adipose‐Derived Stem Cells

Advanced Science, EarlyView.
The 3D culture of human adipose‐derived stem cells (hADSCs) on a crosslinked cyclosiloxane‐based poly‐Z matrix platform enables the formation of spheroid structures enriched with extracellular matrix (ECM). These ECM‐enriched hADSC spheroids cultured on poly‐Z exhibit enhanced differentiation potential, immunomodulatory capacity, and in vivo ...
Changjin Seo, Dohyeon Kim, Junhyuk Song, Sun‐Young Kim, Youngju Son, Afia Tasnim Rahman, Sangyong Jon   +6 more
wiley   +1 more source

Solid oxide fuel cell simulation model tuning using operating conditions dependent optimization techniques. [PDF]

Sci Rep
Hesham H, Abdel Rahman M, Bassioni G, Swief RA, Ezzat M, Helmy S, Elbehairy NM.   +6 more
europepmc   +1 more source

Anterior release & posterior spinal fusion vs. posterior-only fusion in AIS patients with large magnitude thoracic curves. [PDF]

Eur J Orthop Surg Traumatol
Permutt A, Silk Z, Leong J, Noordeen H, Lehovsky J, Molloy S, Gibson A, Shafafy R.   +7 more
europepmc   +1 more source

Far-from-equilibrium thermodynamics of the human uterus: A self-organized dissipative structure. [PDF]

Physiol Rep
Lecarpentier Y, Claes V, Krokidis X, Locher C, Hébert JL, Schussler O, Michel F.   +6 more
europepmc   +1 more source

Increased Global Post-Systolic Contraction During 1st Interstage Predicts Medium-Term Death or Transplantation in Children With Hypoplastic Left Heart Syndrome. [PDF]

Echocardiography
Harake D, Kapravelou E, Eckersley L, Tham E, Colen T, Lin L, Shigemitsu S, Beigh M, Moray A, Khoo NS.   +9 more
europepmc   +1 more source

Comparison of N-Terminal Pro-B-Type Natriuretic Peptide Between Cats with Cardiogenic Arterial Thromboembolism and Cats with Occult Cardiomyopathy Without Arterial Thromboembolism. [PDF]

Animals (Basel)
Oranges MA, Freeman LM, Rozanski EA, Karlin ET, Rush JE.   +4 more
europepmc   +1 more source