Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
[Integrated cross-sectoral collaboration for pregnant women and (expectant) parents in a vulnerable situation: the Solid Start integrated approach in South Limburg, the Netherlands]. [PDF]
Smeets-Curvers N +5 more
europepmc +1 more source
Experimental investigation of vehicle's lateral acceleration on highway horizontal curver [PDF]
openaire +1 more source
The study of two-dimensional oscillations using a smartphone acceleration sensor: example of Lissajous curves [PDF]
Luis Tuset-Sanchis +4 more
openalex +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
The relation between Schneiderian membrane thickening and radiodiagnostic features of periapical pathology. [PDF]
Oliveira-Santos N +8 more
europepmc +1 more source
Physiologic impact of circulating RBC microparticles upon blood-vascular interactions [PDF]
Doctor, Allan +2 more
core +2 more sources
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
The degree of the central curve in semidefinite, linear, and quadratic programming
Serkan Hoşten +2 more
openalex +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source

