Results 161 to 170 of about 383 (188)
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Een onderzoek naar een integraal magazijnbeheersingssysteem bij Curver Brunssum
, 1989 openaire +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Een onderzoek naar het terugleggen van het klantenorder-ontkoppelpunt bij Curver NWE
, 1989 openaire +1 more source
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An efficient navigation method using progressive curverization in virtual endoscopy
International Congress Series, 2005Abstract Virtual endoscopy provides visualization of inner surface of the human organ using three dimensional volume models. Fast and accurate path generation and navigation in virtual endoscopy is the most important feature. We propose a real-time navigation method that computes camera position and makes a continuous curved path in ray-casting step.
Koo-Joo Kwon, Byeong-Seok Shin
openaire +1 more source
Measuring retrospective user experience of non-powered hand tools
Proceedings of the 18th International Academic MindTrek Conference: Media Business, Management, Content & Services, 2014User experience (UX) can change over time, when the exciting new product becomes an ordinary part of daily life. With experiences, also our evaluation of a product can change, affecting whether we will recommend the product for others. Studying the long-term UX of products with retrospective methods offers an alternative to the resource demanding real ...
Sahar Farrukh, Varsaluoma Jari
openaire +1 more source
What's In A Name? Curver Luxembourg and Its Implications for Design Patents
SSRN Electronic Journal, 2020This Article examines design patent law in the context of the 2019 Court of Appeals for the Federal Circuit decision of Curver Luxembourg, SARL v. Home Expressions, Inc. It first explains the law of design patents as it was prior to the Curver Luxembourg decision — providing an overview of the three key requirements for design patent eligibility, the ...
openaire +1 more source