Results 141 to 150 of about 11,283 (172)
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La Presse Médicale, 2021
Cushing's disease (CD) is the most prevalent cause of endogenous hypercortisolism. CD is responsible for multiple co-morbidities and increased mortality. Accurate and prompt diagnosis and optimal treatment are essential to improve the prognosis of CD.
Francesca Pecori Giraldi +1 more
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Cushing's disease (CD) is the most prevalent cause of endogenous hypercortisolism. CD is responsible for multiple co-morbidities and increased mortality. Accurate and prompt diagnosis and optimal treatment are essential to improve the prognosis of CD.
Francesca Pecori Giraldi +1 more
openaire +3 more sources
Pituitary, 2006
Cushing's disease, i.e., pituitary ACTH-secreting adenoma causing excess glucocorticoid secretion, is a rare disease with significant mortality and morbidity. Timely diagnosis and appropriate treatment can alter the course of the disease and are therefore mandatory.
M. De Martin +2 more
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Cushing's disease, i.e., pituitary ACTH-secreting adenoma causing excess glucocorticoid secretion, is a rare disease with significant mortality and morbidity. Timely diagnosis and appropriate treatment can alter the course of the disease and are therefore mandatory.
M. De Martin +2 more
openaire +2 more sources
The American Journal of Surgery, 1960
Abstract The presenting complaint of this patient with Cushing's syndrome was a very severe infection of the leg. Hypertension, cardiomegaly, osteoporosis, impaired glucose tolerance, electrolyte disturbances and the physical appearance of the syndrome have been reversed following total adrenalectomy.
E J, CARRY, I, WALZER
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Abstract The presenting complaint of this patient with Cushing's syndrome was a very severe infection of the leg. Hypertension, cardiomegaly, osteoporosis, impaired glucose tolerance, electrolyte disturbances and the physical appearance of the syndrome have been reversed following total adrenalectomy.
E J, CARRY, I, WALZER
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Best Practice & Research Clinical Endocrinology & Metabolism, 2009
Cushing's syndrome refers to the clinical manifestations induced by chronic exposure to excess glucocorticoids. There are three pathological conditions that can result in the chronic overproduction of endogenous cortisol in man: the most frequent is Cushing's disease where adrenocorticotropic hormone (ACTH) is overproduced by a pituitary corticotroph ...
Xavier, Bertagna +3 more
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Cushing's syndrome refers to the clinical manifestations induced by chronic exposure to excess glucocorticoids. There are three pathological conditions that can result in the chronic overproduction of endogenous cortisol in man: the most frequent is Cushing's disease where adrenocorticotropic hormone (ACTH) is overproduced by a pituitary corticotroph ...
Xavier, Bertagna +3 more
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2014
Cushing's disease (CD) is caused by a pituitary tumor secreting corticotropin (ACTH), leading to cortisol excess. Patients with CD comprise approximately 70% of patients with endogenous Cushing's syndrome (CS). If the diagnosis and treatment are delayed, patients with CD may suffer the deleterious consequences of hypercortisolism, leading to ...
Nicholas A, Tritos, Beverly M K, Biller
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Cushing's disease (CD) is caused by a pituitary tumor secreting corticotropin (ACTH), leading to cortisol excess. Patients with CD comprise approximately 70% of patients with endogenous Cushing's syndrome (CS). If the diagnosis and treatment are delayed, patients with CD may suffer the deleterious consequences of hypercortisolism, leading to ...
Nicholas A, Tritos, Beverly M K, Biller
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Harvey Cushing: Cushing's Disease
Journal of Perioperative Practice, 2012In 1932 Harvey Cushing published an article entitled ‘Basophil adenomas of the pituitary and their clinical manifestations'. These are rare tumours of the anterior pituitary gland, at the base of the brain, with striking manifestations, which include adiposity of the face and trunk, but not the limbs, weakness, fatigue, abdominal striae, facial hair ...
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The American Journal of Surgery, 1979
Harvey Cushing [I] presented and subsequently published his extraordinary study of basophilic pituitary adenomas in 1932. Validation of these observations followed long after his death through the fortunate coincidence of two developments: first, conclusive biochemical definition of pituitary-based hypercortisolism, for the first time differentiating ...
C B, Wilson, J B, Tyrrell, P, Fitzgerald
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Harvey Cushing [I] presented and subsequently published his extraordinary study of basophilic pituitary adenomas in 1932. Validation of these observations followed long after his death through the fortunate coincidence of two developments: first, conclusive biochemical definition of pituitary-based hypercortisolism, for the first time differentiating ...
C B, Wilson, J B, Tyrrell, P, Fitzgerald
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Diagnosis of Cushing’s disease
Pituitary, 2015Diagnosis of Cushing's disease frequently remains a challenge. In this review we critically appraise the clinical features, biochemical tests, and imaging modalities used for this purpose. We outline recommendations for approaches to clinical investigation, with a particular focus on developments made within the last two years.
Eleni, Daniel, John D C, Newell-Price
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Nature Reviews Endocrinology, 2011
Cushing disease is caused by a corticotroph tumor of the pituitary gland. Patients with Cushing disease are usually treated with transsphenoidal surgery, as this approach leads to remission in 70-90% of cases and is associated with low morbidity when performed by experienced pituitary gland surgeons.
Nicholas A, Tritos +2 more
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Cushing disease is caused by a corticotroph tumor of the pituitary gland. Patients with Cushing disease are usually treated with transsphenoidal surgery, as this approach leads to remission in 70-90% of cases and is associated with low morbidity when performed by experienced pituitary gland surgeons.
Nicholas A, Tritos +2 more
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Endocrinología y Nutrición (English Edition), 2014
The aim of this study was to review the literature published and the most important papers presented to meetings on Cushing's disease from October 2011 to September 2012. The selection has been performed according to the authors' criteria. Articles have been classified into five groups: quality of life and perception of the disease, clinical features ...
Gabriel, Obiols Alfonso +3 more
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The aim of this study was to review the literature published and the most important papers presented to meetings on Cushing's disease from October 2011 to September 2012. The selection has been performed according to the authors' criteria. Articles have been classified into five groups: quality of life and perception of the disease, clinical features ...
Gabriel, Obiols Alfonso +3 more
openaire +2 more sources