Results 101 to 110 of about 24,911 (211)

Long-term low-dose ketoconazole treatment in bilateral macronodular adrenal hyperplasia [PDF]

, 2014
Medical therapy for Cushing's syndrome due to bilateral macronodular adrenal hyperplasia (BMAH) is generally administered for a limited time before surgery.
Comte-Perret, S., Gomez, F., Zanchi, A.
core   +1 more source

Very Long‐Term Follow‐Up of Multidimensional Health‐Related Quality of Life After Endoscopic Endonasal Surgery for Pituitary Adenomas: A Prospective Cohort Study

Head &Neck, Volume 48, Issue 4, Page 1088-1096, April 2026.
ABSTRACT Background To evaluate postoperative health‐related quality of life (HRQoL) for pituitary adenoma patients, multidimensional assessment is important. Available data is limited on long‐term follow‐up. Methods Prospectively, 52 nonfunctioning (NFA) and functioning (FA) pituitary adenoma patients were included.
Gonneke E. Joustra, Nathalie F. van Rhee, Marc C. den Heijer, Astrid G. W. Korsten‐Meijer, Robert A. Feijen, György B. Halmos, Jos M. A. Kuijlen, Karin M. Vermeulen   +7 more
wiley   +1 more source

The gut microbiome in patients with Cushing’s disease affects depression- and anxiety-like behavior in mice

Microbiome
Background Depression and anxiety significantly impact the quality of life in individuals with Cushing’s disease (CD), which originates from pituitary neuroendocrine tumors (PitNETs), yet our understanding of the underlying mechanisms is limited.
Ding Nie, Dawei Wang, Zhenhua Wang, Qiuyue Fang, Hongyun Wang, Weiyan Xie, Chuzhong Li, Yazhuo Zhang   +7 more
doaj   +1 more source

Metyrapone for Long-Term Medical Management of Cushing’s Syndrome

Case Reports in Endocrinology, 2013
Cushing’s syndrome is characterized by any cause of excess cortisol in the blood and produces many physiologic consequences. Left untreated, Cushing’s is associated with significant morbidity and mortality.
Andrea N. Traina, Ashley Farr, Ritu Malik, Robert J. Bingham   +3 more
doaj   +1 more source

Endothelial progenitor cells in a patient with Cushing's syndrome before and after adrenal surgery

Journal of Clinical and Translational Endocrinology Case Reports, 2018
Endothelial progenitor cells (EPCs) exert a pivotal role in vascular repairing and vascular function. Low EPCs levels have been detected in patients with endocrine disease at increased cardiovascular risk such as diabetes, hypothyroidism, and ...
Roberto Negro
doaj   +1 more source

No evidence for oncogenic mutations in guanine nucleotide-binding proteins of human adrenocortical neoplasms [PDF]

, 1933
G-Proteins are membrane-bound heterotrimeric polypeptides that couple receptor signals to second messenger systems such as cAMP. Recently, point mutations at 2 codons of the highly preserved alpha-chain of Gs, the adenyl cyclase-stimulating G-protein ...
Chrousos, G. P., Karl, M., Reincke, Martin, Travis, W.   +3 more
core  

Somatostatin receptor scintigraphy: Its value in tumor localization in patients with Cushing's syndrome caused by ectopic corticotropin or corticotropin-releasing hormone secretion [PDF]

, 1994
purpose: To assess the feasibility of somatostatin receptor scintigraphy for patients with Cushing's syndrome caused by tumors secreting ectopic corticotropin or corticotropin-releasing hormone (CRH).
Bruining, H.A. (Hajo), Herder, W.W. (Wouter) de, Hofland, L.J. (Leo), Kreniming, E.P. (Eric), Kwekkeboom, D.J. (Dirk Jan), Lamberts, S.W.J. (Steven), Malchoff, C.D. (Carl), Nobels, F.R.E. (Frank), Oei, H.Y. (H.), Pols, H.A.P. (Huib), Reubi, J.-C. (Jean-Claude)   +10 more
core   +1 more source

Clinical Practice Patterns in Bone Health Assessment and Management in Endogenous Cushing's Syndrome

Clinical Endocrinology, Volume 104, Issue 4, Page 302-311, April 2026.
ABSTRACT Objective Skeletal fragility is a common complication of endogenous Cushing's Syndrome (CS), although specific guidelines for managing bone health are lacking. This study aimed to assess clinicians' current engagement with bone health assessment and management in patients with endogenous CS. Design Retrospective‐cohort design. Patients Seventy‐
Preeshila Behary, Dinushan Raveendran, Ramesh Nair, Aimee Di Marco, Debbie Papadopoulou, Florian Wernig, Ali Abbara, Karim Meeran, Niamh Martin, Jeremy Cox, Alexander N. Comninos   +10 more
wiley   +1 more source

Asynchronous Rhythm of Steroidogenic Factor 1 and Period Homolog 2 mRNA Expression in Mouse Y1 Adrenocorticol Tumor Cells [PDF]

, 2010
The relationship between the expression of Steroidogenic factor 1 (Sf1) and the circadian-related gene, period homolog 2 (Per2), in the adrenal cortex is still unknown.
Hajime Nawata, Kenji Ohe, Koichi Node, Koichi Oba, Kouichirou Sonoda, Makoto Akashi, Masatoshi Nomura, Ryoichi Takayanagi, Taijiro Okabe, Toshihiko Yanase   +9 more
core   +1 more source

Patients With Pituitary Neuroendocrine Tumours Requiring Neurosurgery –Who Is Referring Them?

Clinical Endocrinology, Volume 104, Issue 4, Page 352-361, April 2026.
ABSTRACT Objective Patients living with pituitary neuroendocrine tumours (PitNETs) present with a spectrum of clinical manifestations and often follow a circuitous route to diagnosis, resulting in diagnostic delays. The objective of this study is to identify and report the various sources of referrals for patients who underwent pituitary resection for ...
Doua S. Ahmed, Brian Herron, Stephen Cooke, Philip Weir, Jane Evanson, Estelle G. Healy, Karen R. Mullan, Stephanie G. Craig, Jacqueline A. James, Márta Korbonits, Steven J. Hunter, Paul Benjamin Loughrey   +11 more
wiley   +1 more source