Results 101 to 110 of about 25,174 (219)
Kinetics and Inhibition Studies of the L205R Mutant of cAMP-Dependent Protein Kinase Involved in Cushing’s Syndrome [PDF]
, 2018 Overproduction of cortisol by the hypothalamus–pituitary–adrenal hormone system results in the clinical disorder known as Cushing\u27s syndrome. Genomics studies have identified a key mutation (L205R) in the α‐isoform of the catalytic subunit of cAMP ...
Ellis, Keith C. +3 more
core +2 more sources
Acta Ophthalmologica, EarlyView.Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen +3 more
wiley +1 more source
Radiotherapy in Cushing’s Disease
Endocrinology Research and Practice, 2018 Objectives: To assess tumor growth control, biochemical response, factors affecting remission, and to identify possible complications in Cushing’s Disease (CD) treated with radiotherapy (RT).
Hande Mefkure Özkaya +2 more
doaj +1 more source
Managing Cushing's disease: the state of the art. [PDF]
, 2014 Cushing's disease is a rare chronic disease caused by a pituitary adenoma, which leads to excess secretion of adrenocorticotropic hormone (ACTH). The over-production of ACTH leads to hyperstimulation of the adrenal glands and a chronic excess of cortisol,
Boscaro M +3 more
core +1 more source
Clinical Obesity, Volume 15, Issue 2, April 2025.Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton +4 more
wiley +1 more source
Glucocorticoid regulation of food-choice behavior in humans: Evidence from Cushing’s syndrome
Frontiers in Neuroscience, 2016 The mechanisms by which glucocorticoids regulate food intake and resulting body mass in humans are not well-understood. One potential mechanism could involve modulation of reward processing, but human stress models examining effects of glucocorticoids on
Scott J Moeller +8 more
doaj +1 more source
Efeito do tratamento com ketoconazole por um mês na liberação de GH, cortisol e ACHT após administração de GHrelin, GHRP-6 e GHRH em pacientes com síndrome de cushing [PDF]
, 2007 GH responses to ghrelin, GHRP-6, and GHRH in Cushing s disease (CD) are markedly blunted. There is no data about the effect of reduction of cortisol levels with steroidogenesis inhibitors, like ketoconazole, on GH secretion in CD.
Correa-Silva, Silvia R. +4 more
core +3 more sources
Estimating the total mortality of seabirds following a marine heat wave
Conservation Biology, EarlyView.Abstract Marine heat waves detrimentally affect a range of marine species, including seabirds, and are increasing in frequency and severity. When thousands of dead seabirds wash up on beaches, the public becomes concerned. However, the number of dead birds recorded on beaches is only a fraction of the total mortality; most birds perish at sea.
Jennifer L. Lavers +3 more
wiley +1 more source
Prevalência da hipertensão arterial na síndrome de Cushing.
Acta Médica Portuguesa, 1997 To determine the prevalence of hypertension (HT) in patients with Cushing's syndrome.We studied 23 patients with Cushing's syndrome, 17 women (mean +/- SD age = 42.8 +/- 15.6 years) and 6 men (mean +/- SD age = 34.8 +/- 10.2 years).
D Rodrigues +5 more
doaj +1 more source
Considerations for the Use of AAV‐based Gene Therapy in HIV‐Positive Individuals With Haemophilia
Haemophilia, EarlyView.ABSTRACT Introduction There is a high prevalence of human immunodeficiency virus (HIV) infection among the haemophilia community due to treatment in the 1970s and 1980s with contaminated clotting factor. Lifelong treatment regimens for haemophilia and HIV are burdensome alone and pose a particular challenge for individuals living with both conditions ...
Jürgen K. Rockstroh +5 more
wiley +1 more source