Results 21 to 30 of about 24,911 (211)

Changes in adenosine 5'-monophosphate-activated protein kinase as a mechanism of visceral obesity in Cushing's syndrome [PDF]

, 2008
OBJECTIVE: Features of the metabolic syndrome such as central obesity with insulin resistance and dyslipidemia are typical signs of Cushing's syndrome and common side effects of prolonged glucocorticoid treatment.
Blerina Kola, Mirjam Christ-Crain, Francesca Lolli, Giorgio Arnaldi, Gilberta Giacchetti, Marco Boscaro, Ashley B. Grossman, Márta Korbonits, Kola, Gudbjornsson, van Staa, Walsh, Arnaldi, Mayo-Smith, Kahn, Christ-Crain, Tataranni, Steinberg, Hojlund, Bandyopadhyay, Kola, Hawley, Terzolo, Mantero, Barzon, Bujalska, Seckl, Daval, Wang, Vander Kooi, Shaw, Clark   +31 more
core   +1 more source

Effects of loperamide on the human hypothalamo-pituitary-adrenal axis in vivo and in vitro. [PDF]

, 1992
Loperamide, an opiate agonist of high specificity for p-receptors, was recently reported to suppress ACTH and cortisol levels in normal subjects, but not in patients with proven ACTH-dependent Cushing’s disease. However, there is little information on
Auernhammer, Christoph J., Lange, M., Müller, O.A., Pfeiffer, M., Stalla, G.K.   +4 more
core   +1 more source

An Unusual Case of Cushing’s Syndrome: Coexistence of Functional Pituitary and Adrenal Adenoma

Haseki Tıp Bülteni, 2017
A case of adrenocorticotropic hormone (ACTH)-independent Cushing’s syndrome, which develops in the course of ACTH-dependent Cushing’s disease, is presented in this report.
Muzaffer İlhan, Özcan Karaman, İrem Yasin Çetin, Nur Büyükpınarbaşılı, Jamshid Hamdard, Ertuğrul Taşan   +5 more
doaj   +1 more source

An extremely rare case of calcinosis cutis in human Cushing’s disease

Endocrinology, Diabetes & Metabolism Case Reports, 2022
Cushing’s disease or pituitary adrenocorticotropic hormone (ACTH)-dependent Cushing’s syndrome is considered a rare condition. It is caused by hypersecretion of the ACTH by a pituitary adenoma that ultimately induces endogenous hypercortisolism by ...
Najoua Rbiai, Ikram Mahroug, Nada Zizi, Hanane Latrech   +3 more
doaj   +1 more source

Kinetics and Inhibition Studies of the L205R Mutant of cAMP-Dependent Protein Kinase Involved in Cushing’s Syndrome [PDF]

, 2018
Overproduction of cortisol by the hypothalamus–pituitary–adrenal hormone system results in the clinical disorder known as Cushing\u27s syndrome. Genomics studies have identified a key mutation (L205R) in the α‐isoform of the catalytic subunit of cAMP ...
Ellis, Keith C., Luzi, Nicole M., Lyons, Charles E., Peterson, Darrell L.   +3 more
core   +2 more sources

Differences in the Clinical Presentation of Patients with Adrenocorticotropic Hormone–Dependent Cushing’s Syndrome

Cerrahpaşa Medical Journal
Objective: This study investigated the influence of ectopic and pituitary Cushing’s syndrome, diagnosed by sampling the inferior petrosal sinus and cavernous sinus, on comorbidities and clinical complications. Methods: Medical records of patients with
Zehra Kara, Ahmet Numan Demir , Cem Sulu, Pınar Kadıoğlu   +3 more
doaj   +1 more source

Invasive fungal infections in endogenous Cushing’s syndrome

Infectious Disease Reports, 2010
Cushing’s syndrome is a condition characterized by elevated cortisol levels that can result from either augmented endogenous production or exogenous administration of corticosteroids.
Rafael Selbach Scheffel, José Miguel Dora, Letícia Schwerz Weinert, Valério Aquino, Ana Luiza Maia, Luis Henrique Canani, Luciano Z. Goldani   +6 more
doaj   +1 more source

Additional file 1: of Illustration of patient-reported outcome challenges and solutions in rare diseases: a systematic review in Cushingâ s syndrome

, 2018
Summary table type of PRO and study design per reference. A table summarizing the type of PRO and study design per reference. (DOCX 27 kb)
Knoble, Naomi, Nayroles, Gabrielle, Cheng, Cherry, Benoit Arnould   +3 more
openaire   +1 more source

Fluconazole for Hypercortisolism in Cushing’s Disease: A Case Report and Literature Review

Frontiers in Endocrinology, 2020
BackgroundCushing’s disease is associated with an increased risk of pulmonary fungal infection, which could be a relative contraindication for pituitary adenoma excision surgery.CaseWe report a case of a patient with Cushing’s disease and pulmonary ...
Yiming Zhao, Weiwei Liang, Feng Cai, Qun Wu, Yongjian Wang   +4 more
doaj   +1 more source

Additional file 2: of Illustration of patient-reported outcome challenges and solutions in rare diseases: a systematic review in Cushingâ s syndrome

, 2018
Sub-domains of PRO assessed per PRO. A table summarizing the sub-domains of PRO assessed per PRO. (DOCX 18 kb)
Knoble, Naomi, Nayroles, Gabrielle, Cheng, Cherry, Benoit Arnould   +3 more
openaire   +1 more source