Does an Analysis of the Pulsatile Secretion Pattern of Adrenocorticotropin and Cortisol Predict the Result of Transsphenoidal Surgery in Cushing’s Disease. [PDF]
The endocrinological, surgical, and histological findings of patients with ACTH-dependent Cushing's disease were correlated with the pulsatile secretion pattern of ACTH and cortisol and the outcome after transsphenoidal pituitary surgery.
Brabant, Georg +5 more
core +1 more source
Effects of loperamide on the human hypothalamo-pituitary-adrenal axis in vivo and in vitro. [PDF]
Loperamide, an opiate agonist of high specificity for p-receptors, was recently reported to suppress ACTH and cortisol levels in normal subjects, but not in patients with proven ACTH-dependent Cushing’s disease. However, there is little information on
Auernhammer, Christoph J. +4 more
core +1 more source
New directions for the treatment of adrenal insufficiency [PDF]
The following funding bodies supported this work: Biotechnology and Biological Sciences Research Council (BBSRC BB/L00267/1, to LG), Rosetrees Trust (to LG), Barts and The London Charity (417/2235, to LG), EU COFUND (PCOFUND-GA-2013-608765, to LG and GRB)
Allen +69 more
core +5 more sources
A rare case of an ACTH/CRH co-secreting midgut neuroendocrine tumor mimicking Cushing’s disease
Ectopic ACTH/CRH co-secreting tumors are a very rare cause of Cushing’s syndrome and only a few cases have been reported in the literature. Differentiating between Cushing’s disease and ectopic Cushing’s syndrome may be particularly difficult if ...
Regina Streuli +7 more
doaj +1 more source
Changes in adenosine 5'-monophosphate-activated protein kinase as a mechanism of visceral obesity in Cushing's syndrome [PDF]
OBJECTIVE: Features of the metabolic syndrome such as central obesity with insulin resistance and dyslipidemia are typical signs of Cushing's syndrome and common side effects of prolonged glucocorticoid treatment.
Blerina Kola +31 more
core +1 more source
Retrospective Analysis of Cushing’s Disease with or without Hyperprolactinemia
Objective. We compared the characteristics of patients with Cushing’s disease alone with those of patients with Cushing’s disease and hyperprolactinemia. Methods. Eighty-four patients were enrolled between 2002 and 2011, in a hospital in China. Clinical,
Cheng Huan +4 more
doaj +1 more source
Hyperglycemia induced by pasireotide in patients with Cushing’s disease or acromegaly [PDF]
PURPOSE: Cushing’s disease (CD) and acromegaly are characterized by excessive hormone secretion resulting in comorbidities such as impaired glucose metabolism, diabetes and hypertension.
Silverstein, Julie M
core +2 more sources
Clinical periodontal diagnosis
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi +5 more
wiley +1 more source
Diagnosis аnd neurosurgical treatment of Cushing’s disease
The informing of existing diagnostic methods was determined. The optimal algorithm for Cushing’s disease diagnostics was developed. The efficacy of neurosurgical treatment of pituitary adenomas at Cushing’s disease was estimated.
Aleksandr Guk +10 more
doaj +1 more source
Cardiovascular features of possible autonomous cortisol secretion in patients with adrenal incidentalomas [PDF]
Background: Low-grade incomplete post-dexamethasone cortisol suppression in patients with adrenal incidentalomas – recently defined as possible autonomous cortisol secretion (pACS) – has been associated with increased cardiovascular events and mortality.
Di Giorgio, Maria Rosaria +12 more
core +2 more sources

