Results 71 to 80 of about 24,911 (211)

Systemic Absorption and Pharmacokinetics of Five Novel Topical Dermatologic Agents: A Review

JEADV Clinical Practice, EarlyView.
ABSTRACT In recent years, innovative topical medications with novel mechanisms of action have emerged to treat common dermatologic conditions such as acne, atopic dermatitis, vitiligo, and actinic keratoses. These molecularly targeted therapies offer improved safety and tolerability compared to traditional options like corticosteroids.
Mary Dyson, Kara Hurley, Hannah Chaudhury, Lara Shehadeh, Cameron West   +4 more
wiley   +1 more source

Adrenocorticotropic hormone levels before treatment predict recurrence of Cushing's disease [PDF]

, 2015
Background/PurposeCushing's disease (CD) is the most common cause of endogenous Cushing's syndrome. Transsphenoidal surgery (TSS) is the first choice of treatment.
Stewart, Plotz, Cushing, Lambert, Pivonello, Clayton, Hassan-Smith, Chee, Lindsay, Trainer, Chen, Estrada, Losa, Nishizawa, van Aken, Atkinson, Hammer, Rees, Leowattana, McKenna, Burkhardt, Rebuffe-Scrive, Wajchenberg, Geer, Valassi, Toms, Pereira   +26 more
core   +3 more sources

The missing woodland story: Implications of 1700 years of stand‐scale change on ‘naturalness’ and managing remnant broadleaved woodlands

People and Nature, EarlyView.
Abstract Longer‐term perspectives—equivalent to the lifespans of long‐lived trees—are required to fully inform perceptions of ‘naturalness’ used in woodland conservation and management. Stand‐scale dynamics of an old growth temperate woodland are reconstructed using palaeoecological data.
Annabel Everard, J. Edward Schofield, Tim Mighall, Scott Timpany, Gill Plunkett   +4 more
wiley   +1 more source

Development and evaluation of a health‐related quality‐of‐life tool for dogs with Cushing's syndrome

Journal of Veterinary Internal Medicine, 2019
Background Clinical signs and consequences of Cushing's syndrome are likely to impact upon a dog's life. Quantification of this impact on a dog's health‐related quality‐of‐life (HRQoL) could contribute to optimized disease management.
Imogen Schofield, Dan G. O'Neill, Dave C. Brodbelt, David B. Church, Rebecca F. Geddes, Stijn J. M. Niessen   +5 more
doaj   +1 more source

Using a social‐ecological macrosystems framework to understand how human activities alter ecological synchrony

People and Nature, EarlyView.
Abstract Different aspects of ecological systems, biotic or abiotic, often fluctuate in coordinated patterns over space and time. Such high concordance between ecological processes is often referred to as ecological synchrony. Human activities, including and beyond climate change, have the potential to alter ecological synchrony by disrupting or ...
Yiluan Song, Mallory Barnes, K. Ann Bybee‐Finley, Kyla M. Dahlin, Travis McDevitt‐Galles, Stephan B. Munch, Guillermo E. Ponce‐Campos, Casey Youngflesh, Benjamin Zuckerberg, Kai Zhu   +9 more
wiley   +1 more source

Pasireotide can induce sustained decreases in urinary cortisol and provide clinical benefit in patients with Cushing’s disease: results from an open-ended, open-label extension trial [PDF]

, 2014
International audiencePurpose Report the efficacy and safety of pasireotide sc in patients with Cushing's disease during an open-ended, open-label extension to a randomized, double-blind, 12-month, Phase III study.
Boscaro, Marco, Gareth, Hughes, Gu, Feng, Jerome, Bertherat, Ligueros-Saylan, Monica, Pivonello, Rosario, Rubens, Robert, Salgado, Luiz, Schopohl, Jochen, Trovato, Andrew, Van Gaal, Luc   +10 more
core   +4 more sources

Evaluation of systemic consequences of brachycephalic obstructive airway syndrome in dogs

Veterinary Record, EarlyView.
Abstract Background Brachycephalic obstructive airway syndrome (BOAS) results from upper airway anatomical abnormalities and may cause systemic effects depending on severity. Methods A prospective, case‒control and observational study was conducted.
Andréia Coutinho Facin, Ariadne Rein, Isabella de Almeida Fabris, Beatriz Gasser, Luiz Paulo Nogueira Aires, Bruna Bressianini Lima, Daniele Azevedo Gandra, Daniela Gomes da Silva, Ricardo Andrés Ramirez Uscategui, Gabriela Castro Lopes Evangelista, Marcus Antônio Rossi Feliciano, Paola Castro Moraes   +11 more
wiley   +1 more source

Cushing’s disease – Same condition, different scenarios [PDF]

Archives of the Balkan Medical Union, 2018
Cushing’s disease is a rare pathology characterized by excess production of adrenocorticotropic hormone (ACTH) secondary to a pituitary adenoma which stimulates adrenal cortisol secretion.
Adina Ghemigian, Andra Cocolos, Paul Neagu, Nicoleta Dumitru, Simona E. Albu, Mara Carsote   +5 more
doaj  

Somatostatin and dopamine receptors as targets for medical treatment of Cushing's Syndrome [PDF]

, 2008
Somatostatin (SS) and dopamine (DA) receptors are widely expressed in neuroendocrine tumours that cause Cushing's Syndrome (CS). Increasing knowledge of specific subtype expression within these tumours and the ability to target these receptor subtypes ...
A Colao, A Colao, A Newman-Tancredi, A Saiardi, A Saveanu, A Saveanu, A Schonbrunn, AB Atkinson, AM Isidori, AM O’Carroll, AS Mahmoud-Ahmed, B Ambrosi, B Ueberberg, C Bruns, C Garcia, C Invitti, C Missale, C Missale, C. de Bruin, D Cervia, D Cervia, D Ferone, D Gaitan, D Morris, D Yin, DC Danila, DL Batista, DN Orth, DW Ray, E Mezey, F Amenta, F Castinetti, F Illouz, F Kelestimur, F Vignati, G Giustina, G Weckbecker, GI Uwaifo, GK Stalla, HA Schmid, HA Schmid, HL Fehm, I Ilias, I Shraga-Slutzky, J Hoek van der, J Hoek van der, J Jagannathan, J Kraicer, J Lindholm, J Newell-Price, J Stack, JB Tyrrell, JC Reubi, JM Farah Jr., JW Miller, KD Wu, L Petrini, L Stefaneanu, L. J. Hofland, LA Casulari, LJ Hofland, LJ Hofland, LJ Hofland, LK Nieman, M Locatelli, M Phlipponneau, M Rocheville, M Tallent, ME Molitch, ML Vance, MR Brown, MZ Strowski, N Unger, N Unger, P Barnett, P Brazeau, P Jaquet, P Jaquet, P Ma, P Petrossians, PJ Stafford, R Day, R Hall, R Pivonello, R Pivonello, R Pivonello, R Pivonello, R Pivonello, R Pivonello, R Pivonello, R Schade, R Zanettini, R. A. Feelders, RJ Benveniste, RJ Croughs, S. W. J. Lamberts, SL Lightman, SW Lamberts, SW Lamberts, SW Lamberts, SW Lamberts, SW Lamberts, SW Lamberts, SW Lamberts, SW Lamberts, SW Lamberts, SW Lamberts, T Antakly, T Miyoshi, UI Richardson, VG Rasmussen, WE Farrell, WW Herder de, WW Herder de, X Bertagna, YC Patel   +115 more
core   +4 more sources

Surgical Management of Zollinger‐Ellison Syndrome in Multiple Endocrine Neoplasia Type 1 an AFCE and GTE Cohort Study. (Association Francophone de Chirurgie Endocrinienne and Groupe d'étude des Tumeurs Endocrines)

World Journal of Surgery, EarlyView.
To describe surgical indications, procedures and outcomes in patients operated for Zollinger‐Ellison syndrome (ZES) in multiple endocrine neoplasia type 1 (MEN1) using a large nationwide cohort. ABSTRACT Objective To describe surgical indications, procedures and outcomes in patients operated for Zollinger‐Ellison syndrome (ZES) in multiple endocrine ...
Sébastien Gaujoux, François Pattou, Guillaume Cadiot, Mustapha Adham, Philippe Bachellier, Jean‐Pierre Bail, Robert Caiazzo, Nicolas Carrere, Philippe Chaffanjon, Sophie Deguelte, Gianluca Donatini, Bertrand Dousset, Matthieu Faron, Caroline Gronnier, Bruno Heyd, Jean‐Christophe Lifante, Jean Lubrano, Nicolas Meurisse, Eric Mirallié, Nicolas Santucci, Alain Sauvanet, Frédéric Sebag, Laurent Sulpice, Baudoin Thebault, Jean‐Jacques Tuech, Thomas Walter, Christine Binquet, Pierre Goudet   +27 more
wiley   +1 more source