Results 41 to 50 of about 24,187 (191)
BMC Musculoskeletal Disorders, 2023 Background Cushing’s syndrome is known as an important cause of secondary osteoporosis, characterized by reduction of bone mineral density and potential occurrence of fragility fractures before diagnosis in young population. Therefore, for young patients
Jie Cheng, Songli Ju, Zihan Zhang
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Український Журнал Нефрології та Діалізу, 2023 Paraneoplastic syndromes can serve as initial indicators of malignancy, with small cell lung cancer accounting for 13% of new lung cancer diagnoses.
Esra Geçgel +4 more
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Extra-adrenal regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1:physiological regulator and pharmacological target for energy partitioning [PDF]
, 2007 The major glucocorticoid in man, cortisol, plays important roles in regulating fuel metabolism, energy partitioning and body fat distribution.
Alberts +14 more
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International Journal of Endocrinology, 2021 Background. Glucose metabolism is frequently impaired in patients with Cushing’s syndrome (CS) due to chronic exposure to excess glucocorticoids. Inflammation plays an essential role in the pathophysiology of diabetes mellitus (DM).
Baomin Wang +3 more
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Cushing’s syndrome: An overview
Journal of Nepal Medical Association, 2006 Cushing’s syndrome is the collection of symptoms and signs caused by chronic elevation of circulating free cortisol. Since the first description of the syndrome, results from long-term exposure to glucocorticoids has not been improved upon, but our ...
R Cincu, Amit Agrawal
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Kinetics and Inhibition Studies of the L205R Mutant of cAMP-Dependent Protein Kinase Involved in Cushing’s Syndrome [PDF]
, 2018 Overproduction of cortisol by the hypothalamus–pituitary–adrenal hormone system results in the clinical disorder known as Cushing\u27s syndrome. Genomics studies have identified a key mutation (L205R) in the α‐isoform of the catalytic subunit of cAMP ...
Ellis, Keith C. +3 more
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Arthritis Care &Research, EarlyView.Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi +4 more
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Hyperglycemia induced by pasireotide in patients with Cushing’s disease or acromegaly [PDF]
, 2016 PURPOSE: Cushing’s disease (CD) and acromegaly are characterized by excessive hormone secretion resulting in comorbidities such as impaired glucose metabolism, diabetes and hypertension.
Silverstein, Julie M
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Advanced Science, EarlyView.Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao +13 more
wiley +1 more source
High recovery rate of adrenal function after successful surgical treatment of Cushing’s syndrome
Endocrine ConnectionsContext: Successful first-line treatment of Cushing’s syndrome by resection of the underlying tumor is usually followed by adrenal insufficiency. Purpose: The aims of this study were to determine the recovery rate and time to recovery of adrenal function
Annenienke C van de Ven +6 more
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