Results 71 to 80 of about 11,758 (132)
ABSTRACT Introduction Adrenal incidentalomas (AI) are commonly found on imaging done for indications other than to assess the adrenal glands. Prevalence increases with age and is around 10% in people over 80 years. The majority of AIs are benign adenomas, with 20%−50% exhibiting mild autonomous cortisol secretion (MACS).
Alan Kelsall +4 more
wiley +1 more source
Etomidate in the control of severe Cushing's syndrome by neuroendocrine carcinoma
Key Clinical Message Etomidate is a very effective drug in severe Cushing's syndrome that is refractory to ketoconazol. Control of the serum cortisol levels in ectopic Cushing's syndrome can be obtained with infusion rates much lower than those used in ...
Alfredo Adolfo Reza‐Albarrán +2 more
doaj +1 more source
ABSTRACT Objective Mild autonomous cortisol secretion (MACS) is associated with increased cardiometabolic risk factors including hypertension, type 2 diabetes and dyslipidaemia. By using evening doses of metyrapone, a short‐acting 11‐β hydroxylase inhibitor, it has been shown that it is possible to reset the abnormal circadian cortisol rhythm in MACS ...
Simon Berry +3 more
wiley +1 more source
ABSTRACT Objective Despite an increased cerebrovascular disease risk, the impact of Polycystic Ovary Syndrome (PCOS) on cerebrovascular haemodynamics and function is unknown. This study characterised cerebrovascular haemodynamics and function in women with PCOS versus healthy controls. Design Case‐control study.
Cory T. Richards +13 more
wiley +1 more source
Mitotane is an adrenolytic drug with cytotoxic effects, registered for the treatment of advanced adrenocortical carcinoma (ACC), a rare but aggressive tumour type with a poor prognosis despite treatment. Recently, the oral multi‐kinase inhibitor cabozantinib has shown promising results as a potential second‐line treatment option.
Annemieke M. Peters van Ton +4 more
wiley +1 more source
Based on the integrated analysis of follicular fluid metabolites and microbial communities in patients with PCOS, this study reveals significant dysregulation in the follicular microenvironment. Key metabolites including D‐glucose and 25‐hydroxycholesterol show marked alterations, while microbial communities such as Alicyclobacillus and Terrimonas ...
Manfei Si +6 more
wiley +1 more source
Cushing’s Syndrome due to Ectopic ACTH from Bronchial Carcinoid: A Case Report and Review
Despite advances in analytic and imaging techniques, the syndrome of ectopic adrenocorticotrophic hormone (ACTH) secretion from a tumour resulting in Cushing’s syndrome continues to pose difficult diagnostic and therapeutic challenges.
Manohara Kenchaiah, Steve Hyer
doaj +1 more source
Prolonged survival in a young Dobermann with adrenal neuroblastoma
Abstract A 1‐year‐old Dobermann presented with recurrent episodes of acute diarrhoea and weight loss starting at 5 months of age. An adrenal mass was identified via ultrasound and computed tomography, leading to adrenalectomy. A diagnosis of adrenal neuroblastoma was obtained through histopathology and immunohistochemistry.
Nataliia Ignatenko +8 more
wiley +1 more source
A Retrospective Study on the Impact of Primary Aldosteronism in Pregnancy (H.A.P.P.I. Study Group)
ABSTRACT Objective Primary aldosteronism (PA) is a common cause of hypertension in young women. However, there is a paucity of data regarding its impact during pregnancy. The primary objective of this study was to describe the occurrence of hypertensive disorders of pregnancy (HDP) in PA.
Diana Oprea +7 more
wiley +1 more source

