Abstract Objective While cardiometabolic comorbidities have been well established in adults with polycystic ovary syndrome (PCOS), it remains unclear whether the early signs of cardiovascular morbidity emerge during adolescence. This study aimed to investigate whether metabolic and cardiovascular alterations begin in adolescents with PCOS.
Demet Aygün Ari +8 more
wiley +1 more source
An unusually small pituitary microadenoma causing severe Cushing disease in a male patient: lessons from early Radiosurgical management. [PDF]
Qasim BA +4 more
europepmc +1 more source
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
How Common Is Hypercortisolism in Patients With Type 2 Diabetes? Risk Factors, Epidemiology, and Making a Diagnosis Using a Dexamethasone Suppression Test. [PDF]
Stone JY, Bailey TS.
europepmc +1 more source
MicroRNA–mRNA Networks in Skeletal Muscle of Tailored Pig Models for Dystrophinopathies
ABSTRACT Background Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are X‐linked dystrophinopathies caused by mutations in the dystrophin (DMD) gene. A common DMD‐causing mutation in humans is exon 52 deletion (DMDΔ52), which disrupts the reading frame and abolishes dystrophin expression.
Sarah Reschke +9 more
wiley +1 more source
Hypercortisolism: Causes, Consequences and Clinical Significance - A Review of Pathophysiology. [PDF]
Eldib M, Fierro FE, Abad MO, Correa R.
europepmc +1 more source
Hypertriglyceridemia: Causes, Consequences, Diagnosis, and Management
Hypertriglyceridemia (HTG) arises from the interplay between genetic susceptibility and secondary or precipitating factors, leading to dysregulated triglyceride‐rich lipoprotein (TRL) metabolism. Increased TRL production and impaired clearance promote distinct risk phenotypes: accumulation of apolipoprotein B(apoB)‐containing TRL remnants contributes ...
Shanshan Qi +9 more
wiley +1 more source
A challenging diagnosis of pediatric (cyclic) Cushing disease: the decisive role of hair cortisol. [PDF]
Berkenbosch L, Straetemans S.
europepmc +1 more source
ABSTRACT Objectives To describe temporal trends in the clinical landscape of vitamin K antagonist (VKA) treatment in the Netherlands, after the introduction of a lower international normalized ratio (INR) target range in 2016 and direct oral anticoagulants.
Gilda D. Zielinski +5 more
wiley +1 more source
Management of ectopic Cushing syndrome in medullary thyroid carcinoma: from case reports to systematic literature review. [PDF]
Stanescu LS +6 more
europepmc +1 more source

