Results 211 to 220 of about 48,525 (261)

Cushing's syndrome

open access: yesLancet, The, 2006
Cushing's syndrome results from lengthy and inappropriate exposure to excessive glucocorticoids. Untreated, it has significant morbidity and mortality. The syndrome remains a challenge to diagnose and manage. Here, we review the current understanding of pathogenesis, clinical features, diagnostic, and differential diagnostic approaches.
John Newell-Price   +2 more
exaly   +5 more sources
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Cushing’s response and Cushing’s ulcer

Postgraduate Medical Journal, 2019
A 57-year-old man presented to our service with a 4-month history of clumsiness, unsteady gait and progressive bilateral sensorineural hypoacusia. Neurological examination revealed symmetrical weakness in the lower limbs (power 4/5) with brisk deep tendon reflexes and upgoing plantars.
Charlotte E Griffiths   +2 more
openaire   +2 more sources

Cushing's Syndrome

Endocrinology and Metabolism Clinics of North America, 2008
Cushing's syndrome is a rare endocrine disease characterized by cortisol hypersecretion, induced mainly by a pituitary tumor (Cushing's disease) or, rarely, by an adrenal or an ectopic neuroendocine tumor. Cushing's syndrome is associated with severe morbidities and an increased mortality.
PIVONELLO, ROSARIO   +4 more
openaire   +3 more sources

Cushing’s disease

Pituitary, 2006
Cushing's disease, i.e., pituitary ACTH-secreting adenoma causing excess glucocorticoid secretion, is a rare disease with significant mortality and morbidity. Timely diagnosis and appropriate treatment can alter the course of the disease and are therefore mandatory.
M. De Martin   +2 more
openaire   +2 more sources

Cushing’s syndrome: comparison between Cushing’s disease and adrenal Cushing’s

Endocrine, 2018
The most common etiology of Cushing's syndrome (CS) is an ACTH-producing pituitary adenoma (pitCS), reported as 2-3 times more frequent than primary adrenal CS (adrCS). We aimed to analyze and compare features of patients with pitCS and adrCS.A retrospective file review of 196 consecutive patients (age 46.8 ± 15.6 years, 76% female) diagnosed with CS ...
Dania Hirsch   +8 more
openaire   +2 more sources

Cushing's syndrome

Lancet, The, 2001
During the past 30 years, there have been advances in understanding of the pathogenesis of Cushing's syndrome and in differential diagnosis of its various forms. Improved diagnostic tests and procedures have increased the ability to recognise even mild hypercortisolism and have provided the means to obtain an accurate diagnosis. Despite these advances,
Marco Boscaro   +2 more
exaly   +9 more sources

Harvey Cushing: Cushing's Disease

Journal of Perioperative Practice, 2012
In 1932 Harvey Cushing published an article entitled ‘Basophil adenomas of the pituitary and their clinical manifestations'. These are rare tumours of the anterior pituitary gland, at the base of the brain, with striking manifestations, which include adiposity of the face and trunk, but not the limbs, weakness, fatigue, abdominal striae, facial hair ...
openaire   +2 more sources

Cushing's disease

The American Journal of Surgery, 1960
Abstract The presenting complaint of this patient with Cushing's syndrome was a very severe infection of the leg. Hypertension, cardiomegaly, osteoporosis, impaired glucose tolerance, electrolyte disturbances and the physical appearance of the syndrome have been reversed following total adrenalectomy.
E J, CARRY, I, WALZER
openaire   +2 more sources

Cushing’s syndrome

The Indian Journal of Pediatrics, 1997
Endogenous Cushing's Syndrome (CS) is a relatively uncommon disease in children. The etiology is more often a primary adrenal cause in infants and younger children, and corticotroph adenoma in older ones. Diagnostic evaluation must be stepwise and methodical, aimed at first confirming the presence of the disease, and then looking for the etiology.
openaire   +2 more sources

Cushing's syndrome

BMJ, 2013
A 45 year old woman was being regularly reviewed in primary and secondary care because of a five year history of type 2 diabetes that had required early insulin treatment; refractory hypertension; and subsequent chronic kidney disease. She had previously described other symptoms, including weight gain, bruising, flushes, and low mood, all of which had ...
Julia Kate, Prague   +2 more
openaire   +2 more sources

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