Results 21 to 30 of about 48,525 (261)

Cushing’s disease [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2012
Cushing's disease, or pituitary ACTH dependent Cushing's syndrome, is a rare disease responsible for increased morbidity and mortality. Signs and symptoms of hypercortisolism are usually non specific: obesity, signs of protein wasting, increased blood pressure, variable levels of hirsutism.
Castinetti Frederic   +3 more
openaire   +3 more sources

Diabète endocrine: mise au point à propos d´un cas de maladie de Cushing

open access: yesPAMJ Clinical Medicine, 2020
Le diabète sucré peut survenir au cours de nombreuses endocrinopathies. Il résulte d'un effet direct ou indirect de l'hormone présente en excès sur le métabolisme glucidique. Nous rapportons un cas de diabète secondaire à une maladie de Cushing.
Amadou Diop Dia   +3 more
doaj   +1 more source

Interview by Simon Cushing [PDF]

open access: yes, 2014
Simon Cushing conducted the following interview with Elizabeth Anderson on 18 June ...
Cushing, Simon, Anderson, Elizabeth
core   +1 more source

A patient with Cushing disease lateralizing a pituitary adenoma by inferior petrosal sinus sampling using desmopressin: a case report [PDF]

open access: yesAnnals of Pediatric Endocrinology & Metabolism, 2016
A 14-year-old girl was referred for evaluation of the etiology of Cushing syndrome. During the previous 2 years, she had experienced weight gain, secondary amenorrhea, growth retardation, and back pain.
Joo Hee Lim   +7 more
doaj   +1 more source

The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma

open access: yesNature Communications, 2019
The delivery of single therapeutic microRNAs in brain cancers is challenging. Here, the authors engineer three neuronal microRNAs (miR-124, 128 and 137) into a cluster that, targeting oncogenic chromatin repressors, increases survival of GBM-bearing mice
Vivek Bhaskaran   +15 more
doaj   +1 more source

A Challenging Case of Ectopic Adrenocorticotropin Hormone Syndrome with Bronchial Carcinoid and Literature Review

open access: yesJCRPE
We report an adolescent boy diagnosed with ectopic adrenocorticotropin hormone syndrome (EAS) due to an atypical bronchial carcinoid. The patient was managed by a multidisciplinary team.
Sema Nilay Abseyi   +7 more
doaj   +1 more source

Playing for Keeps: How academic libraries are prioritizing student mental health and well-being through play

open access: yesJournal of Play in Adulthood, 2022
Over the past decade there has been an increasing awareness of the need for wholistic means of support for college and university students. With the rate of mental health concerns continuing to rise, institutions of higher education are working more ...
Megan Kimberley Nance
doaj   +2 more sources

Ectopic Cushing’s syndrome triggering a bipolar affective disorder [PDF]

open access: yesJornal Brasileiro de Psiquiatria
Objective To report the case of a patient with Cushing’s syndrome (CS) resulting from an ectopic tumor producing adrenocorticotropic hormone (ACTH) in an unusual topography, triggering bipolar affective disorder (BAD) in a previously healthy patient ...
Adriano Fernandes de Mendonça   +4 more
doaj   +1 more source

Hypertriglyceridemia in equines with refractory hyperinsulinemia treated with SGLT2 inhibitors

open access: yesOpen Veterinary Journal, 2023
Background: Sodium-Glucose CoTransporter-2 [SGLT2] inhibitors, the -flozin group of drugs, which block glucose reuptake in the renal proximal tubule, are being increasingly used off-label to treat horses with refractory hyperinsulinemia. After two years
Eleanor M. Kellon, Kathleen M. Gustafson
doaj   +1 more source

An Implantable Optogenetics‐Engineered Hydrogel for Amelioration of Rheumatoid Arthritis through Light‐Controlled Metabolic Reprogramming of Synovial Macrophages

open access: yesAdvanced Science, EarlyView.
An implantable hydrogel is designed to enable in situ and on‐demand secretion of GLP‐1 in synovium through blue light irradiation to activate GLP‐1R/HK2/VDAC1 pathway for upregulating tricarboxylic acid cycle and oxidative phosphorylation in macrophage, facilitating tissue repair and bone erosion recovery.
Dahai Hu   +10 more
wiley   +1 more source

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