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Cushing's Syndrome

New England Journal of Medicine, 1995
Cushing's syndrome is usually caused by the secretion of corticotropin or cortisol by a pituitary or adrenal tumor, respectively, or by ectopic secretion of corticotropin. It is possible to determine the specific abnormality in most patients, but it can sometimes be difficult to decide whether the patient has hypercortisolism and whether it is primary ...
openaire   +3 more sources

Metabolic Syndrome in Cushing's Syndrome Patients.

Frontiers of Hormone Research, 2018
Cushing's syndrome (CS), including visceral obesity, dyslipidemia, hypertension and diabetes among its many manifestations, is "a model" of metabolic syndrome.
F. Ferraù, M. Korbonits
semanticscholar   +1 more source

The Cushing Syndromes

Pediatric Clinics of North America, 1990
The 10 years since this journal's last review of CS have seen extraordinary advances in our understanding of many aspects of its causes, diagnosis, and treatment. The spectrum of what are now called the Cushing syndromes has expanded considerably to include CD, multiple sources of ectopic ACTH secretion, and an apparent autoimmune cause.
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Cushing's syndrome

Journal of Surgical Oncology, 2012
AbstractCushing's syndrome (CS) results from prolonged exposure to elevated endogenous cortisol. Majority of cases are caused by ACTH, pituitary, or ectopic origin. Primary adrenal hypersecretion is 15–20% caused by adenomas, carcinomas (ACC), and rarely by nodular adrenocortical disease. CS presents with all typical features.
openaire   +3 more sources

The role of bilateral inferior petrosal sinus sampling in the diagnostic evaluation of Cushing syndrome.

Diagnostic and Interventional Radiology, 2012
Bilateral inferior petrosal sinus sampling is the gold standard diagnostic assay in identifying the pituitary source of adrenocorticotropic hormone secretion in Cushing syndrome.
A. Deipolyi   +6 more
semanticscholar   +1 more source

Cushing’s Syndrome

2020
Cushing’s syndrome is associated with significant morbidity and mortality and should be considered in specific clinical circumstances, including patients who show suggestive symptoms and signs or have incidental adrenal or pituitary lesions. Exogenous glucocorticoid use should always be thoroughly ascertained, as this is the most common cause of ...
Nicholas A. Tritos, Brandon P Galm
openaire   +2 more sources

Structural brain abnormalities in Cushing's syndrome

Current Opinion in Endocrinology, Diabetes & Obesity, 2018
Purpose of review Alongside various physical symptoms, patients with Cushing's disease and Cushing's syndrome display a wide variety of neuropsychiatric and cognitive symptoms, which are indicative of involvement of the central nervous system. The aim of
S. Bauduin   +2 more
semanticscholar   +1 more source

Hyperkortisolismus (Cushing-Syndrom, Morbus Cushing, adrenales Cushing-Syndrom)

2014
Als Cushing-Syndrom bezeichnet man samtliche Zustande pathologisch erhohter und biologisch wirksamer Kortisolspiegel im Blut, einschlieslich medikamentos-induzierter Formen. Als Morbus Cushing wird die zentrale hypothalamisch-hypophysare Form des Hyperkortisolismus bei Hypophysenadenomen bezeichnet. Das adrenale Cushing-Syndrom ist sehr selten und kann
Felix Kawan, Paolo Fornara
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Cushing syndrome

Nature Reviews Disease Primers
Cushing syndrome (CS) is a constellation of signs and symptoms caused by excessive exposure to exogenous or endogenous glucocorticoid hormones. Endogenous CS is caused by increased cortisol production by one or both adrenal glands (adrenal CS) or by elevated adrenocorticotropic hormone (ACTH) secretion from a pituitary tumour (Cushing disease (CD)) or ...
Lynnette K. Nieman   +6 more
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DIAGNOSIS OF ENDOCRINE DISEASE: Differentiation of pathologic/neoplastic hypercortisolism (Cushing's syndrome) from physiologic/non-neoplastic hypercortisolism (formerly known as pseudo-Cushing's syndrome).

European Journal of Endocrinology, 2017
Endogenous hypercortisolism (Cushing's syndrome) usually implies the presence of a pathologic condition caused by either an ACTH-secreting neoplasm or autonomous cortisol secretion from a benign or malignant adrenal neoplasm.
J. Findling, H. Raff
semanticscholar   +1 more source

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