Results 51 to 60 of about 2,086,615 (282)
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Compressed air energy storage in aquifers (CAESA) is a promising technology for large-scale, long-duration energy storage. The initial bubble, also known as cushion gas, is a prerequisite for system operation, as it creates the storage space and provides
Zongyi Li, Chaobin Guo, Qingcheng He
doaj +1 more source
Shale Gas and the EU Internal Gas Market: Beyond the Hype and Hysteria. CEPS Working Document No. 369, September 2012 [PDF]
This paper analyses the interplay between shale gas and the EU internal gas market. Drawing on data presented in the 2012 International Energy Agency’s report on unconventional gas and additional scenario analyses performed by the Joint Research Centre ...
Teusch, Jonas
core
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
EL COJÍN NEUMÁTICO COMO UNA EXPERIENCIA DE LABORATORIO [PDF]
Describes the construction of an air cushion table with a working guide that encourages the development of certain thinking skills which allow greater depth in the concepts through which mental models are descriptions own simulations based on different ...
Greis Julieth Cruz Reyes
doaj
Given the limited dissipating effect and high construction costs of traditional sand cushion in shed, this paper proposes to partially replace the sand with waste tennis balls to solve the problem of poor impact resistance of sand cushion.
Bi, YuZhang +5 more
core +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Impact of Depth on Underground Hydrogen Storage Operations in Deep Aquifers
Underground hydrogen storage in geological structures is considered appropriate for storing large amounts of hydrogen. Using the geological Konary structure in the deep saline aquifers, an analysis of the influence of depth on hydrogen storage was ...
Katarzyna Luboń +2 more
doaj +1 more source
Adaptive Foam 3D Printing of Ultralight and Multifunctional Materials
Adaptive foam 3D printing, enabled by expandable microspheres, imparts cellular structures to thermoplastic and thermosetting polymers, manufactured through a variety of processes including fused filament fabrication, direct ink writing, digital light processing, and inkjet printing.
Nariman Rajabifar, Amir Ameli
wiley +1 more source

