Results 51 to 60 of about 2,086,615 (282)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Influence of Initial Bubble Mass on the Energy Storage Scale and the System Cycle Time in Compressed Air Energy Storage in Aquifers

open access: yesEnergies
Compressed air energy storage in aquifers (CAESA) is a promising technology for large-scale, long-duration energy storage. The initial bubble, also known as cushion gas, is a prerequisite for system operation, as it creates the storage space and provides
Zongyi Li, Chaobin Guo, Qingcheng He
doaj   +1 more source

Shale Gas and the EU Internal Gas Market: Beyond the Hype and Hysteria. CEPS Working Document No. 369, September 2012 [PDF]

open access: yes, 2012
This paper analyses the interplay between shale gas and the EU internal gas market. Drawing on data presented in the 2012 International Energy Agency’s report on unconventional gas and additional scenario analyses performed by the Joint Research Centre ...
Teusch, Jonas
core  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

EL COJÍN NEUMÁTICO COMO UNA EXPERIENCIA DE LABORATORIO [PDF]

open access: yesGondola, 2010
Describes the construction of an air cushion table with a working guide that encourages the development of certain thinking skills which allow greater depth in the concepts through which mental models are descriptions own simulations based on different ...
Greis Julieth Cruz Reyes
doaj  

Experimental study on physical model of waste tennis ball-sand composite shed cushion under rockfall impact

open access: yes, 2022
Given the limited dissipating effect and high construction costs of traditional sand cushion in shed, this paper proposes to partially replace the sand with waste tennis balls to solve the problem of poor impact resistance of sand cushion.
Bi, YuZhang   +5 more
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Impact of Depth on Underground Hydrogen Storage Operations in Deep Aquifers

open access: yesEnergies
Underground hydrogen storage in geological structures is considered appropriate for storing large amounts of hydrogen. Using the geological Konary structure in the deep saline aquifers, an analysis of the influence of depth on hydrogen storage was ...
Katarzyna Luboń   +2 more
doaj   +1 more source

Adaptive Foam 3D Printing of Ultralight and Multifunctional Materials

open access: yesAdvanced Engineering Materials, EarlyView.
Adaptive foam 3D printing, enabled by expandable microspheres, imparts cellular structures to thermoplastic and thermosetting polymers, manufactured through a variety of processes including fused filament fabrication, direct ink writing, digital light processing, and inkjet printing.
Nariman Rajabifar, Amir Ameli
wiley   +1 more source

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