Results 231 to 240 of about 9,877 (349)

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

ChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel, Mohammed Al‐zharani, Lina M. Alneghery, Noha A. Ahmed, Faris F. Aba Alkhayl, Al Mokhtar Lamsabhi   +5 more
wiley   +1 more source

Infective Endocarditis After Endoscopic Stricture Dilation in Crohn's Disease. [PDF]

ACG Case Rep J
Gonçalves A, Barbeiro S, Leal C, Santos A, Vasconcelos H.   +4 more
europepmc   +1 more source

Oncogenic H‐Ras Reprograms Madin‐Darby Canine Kidney (MDCK) Cell‐Derived Midbody Remnant Proteome Following Epithelial‐Mesenchymal Transition

PROTEOMICS, EarlyView.
ABSTRACT Epithelial‐mesenchymal transition (EMT) is a fundamental, dynamic cellular process involved in embryonic development, metastasis, organ fibrosis, and tissue regeneration. To define the molecular landscape of secreted midbody remnants (MBRs) to the EMT process, a proteome analysis of MBRs released from Madin–Darby canine kidney (MDCK) cells and
Adnan Shafiq, Alin Rai, Rong Xu, Maoshan Chen, Wittaya Suwakulsiri, David W. Greening, Richard J. Simpson   +6 more
wiley   +1 more source

Enhancing Precision: Proposed Revision of FDI's 2-Digit Dental Numbering System. [PDF]

Int Dent J
Rajendra Santosh AB, Jones T.
europepmc   +1 more source

Business Organization I (January 18, 1972)

, 1972
William & Mary Law School
core  

Improved Separator for the Incisors, Cuspids and Bicuspids. [PDF]

, 1889
Wendy A. Woodward
openalex  

Implications of impacted mandibular cuspids on mental foramen position

, 2020
Anil Kumar Nagarajappa, Mohammad Khursheed Alam, Abdulelah A. Alanazi, Vinod Bandela, Saif Faruqi   +4 more
openalex   +1 more source

Comparative Digital Estrogen Receptor Alpha (ERα) Expression Analysis in Benign and Malignant Prostate Tissue of Men and Dogs

The Prostate, EarlyView.
ABSTRACT Background The dog is the only large mammal, other than humans, that commonly develops spontaneous prostate cancer (PCa) and is, therefore, considered a valuable model for comparative studies. Estrogens are critical for normal prostate development and contribute to prostatic carcinogenesis in men.
Jennifer Lothion‐Roy, Leonore Aeschlimann, Lea Anna Hiller, Sven Rottenberg, Nigel P. Mongan, Catrin S. Rutland, Emad Rakha, Alexander Dean, Mark A. Rubin, Simone de Brot   +9 more
wiley   +1 more source

Magnetic Resonance Imaging for Dental Pulp Assessment: A Comprehensive Review. [PDF]

J Magn Reson Imaging
Han B, Chen N, Luo J, Afkhami F, Peters OA, Wang X.   +5 more
europepmc   +1 more source